Racine R J, Wilson D A, Gingell R, Sunderland D
Exp Brain Res. 1986;63(1):158-62. doi: 10.1007/BF00235658.
Previous unpublished experiments from this laboratory had revealed only post-activation depression effects in the cerebellar cortex when its inputs were activated by high frequency trains. In the experiments reported in this paper, we found reliable long-term potentiation (LTP) effects in the deep nuclei (interpositus and vestibular) when stimulation trains were applied to the white matter at the point where inferior peduncle fibers enter the cerebellum. LTP effects were found in both acute and chronic preparations. In the chronic preparations, LTP lasted for at least 8 days in all but one animal.
该实验室之前未发表的实验表明，当高频串刺激激活小脑皮质的输入时，仅在小脑皮质中出现激活后抑制效应。在本文报道的实验中，当刺激串施加于下橄榄核纤维进入小脑处的白质时，我们在深部核团（间位核和前庭核）中发现了可靠的长时程增强（LTP）效应。急性和慢性制备中均发现了LTP效应。在慢性制备中，除一只动物外，所有动物的LTP至少持续了8天。
