• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

What do GABA neurons really do? They make possible variability generation in relation to demand.

作者信息

Roberts E

出版信息

Exp Neurol. 1986 Aug;93(2):279-90. doi: 10.1016/0014-4886(86)90189-5.

DOI:10.1016/0014-4886(86)90189-5
PMID:3015658
Abstract

It is proposed that GABA neurons play key roles in maintaining meaningful communications within and among neural units by making possible variability generation in relation to demand. Activities of GABAergic inhibitory projection neurons from command centers and local circuit GABAergic inhibitory interneurons allow adaptive nervous system function to take place in a manner characterized by freedom without license. Through their multiple activities and connections these neurons make possible smooth transitions between modes of nervous system function over a range of increasing demands (neural pressures), enabling organisms to explore full ranges of their options.

摘要

相似文献

1
What do GABA neurons really do? They make possible variability generation in relation to demand.
Exp Neurol. 1986 Aug;93(2):279-90. doi: 10.1016/0014-4886(86)90189-5.
2
GABA neurons in the mammalian central nervous system: model for a minimal basic neural unit.哺乳动物中枢神经系统中的γ-氨基丁酸能神经元:最小基本神经单元模型
Neurosci Lett. 1984 Jun 29;47(3):195-200. doi: 10.1016/0304-3940(84)90513-5.
3
GABA-related phenomena, models of nervous system function, and seizures.γ-氨基丁酸相关现象、神经系统功能模型与癫痫发作
Ann Neurol. 1984;16 Suppl:S77-89. doi: 10.1002/ana.410160713.
4
Inhibitory control of neostriatal projection neurons by GABAergic interneurons.γ-氨基丁酸能中间神经元对新纹状体投射神经元的抑制性控制。
Nat Neurosci. 1999 May;2(5):467-72. doi: 10.1038/8138.
5
Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglia function.基底神经节中GABA功能的模拟:基底神经节功能中GABA能机制的计算模型。
Prog Brain Res. 2007;160:313-29. doi: 10.1016/S0079-6123(06)60018-6.
6
GABAergic control of substantia nigra dopaminergic neurons.黑质多巴胺能神经元的γ-氨基丁酸能调控
Prog Brain Res. 2007;160:189-208. doi: 10.1016/S0079-6123(06)60011-3.
7
Functional diversity and specificity of neostriatal interneurons.新纹状体中间神经元的功能多样性与特异性
Curr Opin Neurobiol. 2004 Dec;14(6):685-92. doi: 10.1016/j.conb.2004.10.003.
8
Oculomotor control in calliphorid flies: GABAergic organization in heterolateral inhibitory pathways.丽蝇的动眼控制:异侧抑制通路中的γ-氨基丁酸能组织
J Comp Neurol. 1995 Oct 16;361(2):298-320. doi: 10.1002/cne.903610208.
9
Propagating activity patterns in large-scale inhibitory neuronal networks.大规模抑制性神经元网络中的传播活动模式
Science. 1998 Feb 27;279(5355):1351-5. doi: 10.1126/science.279.5355.1351.
10
What is GABAergic inhibition? How is it modified in epilepsy?什么是γ-氨基丁酸能抑制?它在癫痫中是如何被改变的?
Epilepsia. 2000;41 Suppl 6:S90-5. doi: 10.1111/j.1528-1157.2000.tb01564.x.

引用本文的文献

1
GABA Receptors and K7 Channels as Targets for GABAergic Regulation of Acetylcholine Release in Frog Neuromuscular Junction.GABA 受体和 K7 通道作为 GABA 能调节蛙类运动终板乙酰胆碱释放的靶点。
Neurochem Res. 2024 Nov 20;50(1):25. doi: 10.1007/s11064-024-04274-x.
2
GABA as a Neurotransmitter in Gastropod Molluscs.γ-氨基丁酸作为腹足纲软体动物中的一种神经递质。
Biol Bull. 2019 Apr;236(2):144-156. doi: 10.1086/701377. Epub 2019 Jan 16.
3
Human breast cancer metastases to the brain display GABAergic properties in the neural niche.
人类乳腺癌脑转移在神经龛中表现出 GABA 能特性。
Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):984-9. doi: 10.1073/pnas.1322098111. Epub 2014 Jan 6.
4
The effects of volatile anesthetics on the extracellular accumulation of [(3)H]GABA in rat brain cortical slices.挥发性麻醉剂对大鼠脑皮质切片中 [(3)H]GABA 细胞外积累的影响。
Cell Mol Neurobiol. 2014 Jan;34(1):71-81. doi: 10.1007/s10571-013-9988-6. Epub 2013 Oct 1.
5
Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships.γ-氨基丁酸能神经传递的药理学和生物化学方面:病理与神经心理生物学关系
Cell Mol Neurobiol. 2004 Dec;24(6):707-28. doi: 10.1007/s10571-004-6913-z.
6
The rhythmic GABAergic system.节律性γ-氨基丁酸能系统。
Neurochem Res. 1998 May;23(5):607-14. doi: 10.1023/a:1022426519297.
7
GABA--the quintessential neurotransmitter: electroneutrality, fidelity, specificity, and a model for the ligand binding site of GABAA receptors.γ-氨基丁酸——典型的神经递质:电中性、保真度、特异性以及γ-氨基丁酸A型受体配体结合位点的模型
Neurochem Res. 1993 Apr;18(4):365-76. doi: 10.1007/BF00967239.
8
Inhibitory actions of motor cortex following unilateral brain lesions as studied by magnetic brain stimulation.通过磁脑刺激研究单侧脑损伤后运动皮层的抑制作用。
Exp Brain Res. 1994;99(1):84-96. doi: 10.1007/BF00241414.
9
GABA-immunoreactive neurons in the photosensory pineal organ of the rainbow trout: two distinct neuronal populations.虹鳟鱼光感受松果体器官中γ-氨基丁酸免疫反应性神经元:两种不同的神经元群体。
Cell Tissue Res. 1987 Oct;250(1):87-92. doi: 10.1007/BF00214658.
10
Presynaptic effects of gamma-aminobutyric acid on norepinephrine release and uptake in rat pineal gland.γ-氨基丁酸对大鼠松果体去甲肾上腺素释放和摄取的突触前效应。
J Neural Transm Gen Sect. 1990;82(2):131-40. doi: 10.1007/BF01245169.