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A U3 RNA pseudogene in mouse: sequence and organization in genomic DNA.

作者信息

Ferrer P, Qu L H, Bouche G, Bachellerie J P

出版信息

FEBS Lett. 1986 Aug 18;204(2):307-12. doi: 10.1016/0014-5793(86)80834-1.

DOI:10.1016/0014-5793(86)80834-1
PMID:3015683
Abstract

A mouse U3 RNA pseudogene has been identified; it corresponds to a U3B full length coding sequence with a 3'-oligo(A) tail, precisely flanked at both ends by a pair of 15 bp direct repeats. These structural features suggest that it has arisen through an RNA-mediated mechanism involving an insertion at staggered nicks in the genome. Sequence data indicate that this mouse specimen has been generated by a different event as compared to the recently described rat pseudogenes. It represents the first reported case, for a pseudogene of this class, to be present at more than one copy per genome.

摘要

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