严重精神疾病患者减肥干预措施的有效性：一项系统评价与荟萃分析。
Effectiveness of Interventions for Weight Loss for People With Serious Mental Illness: A Systematic Review and Meta-Analysis.
作者信息
Brown Catana, Geiszler Lydia C, Lewis Kelsie J, Arbesman Marian
机构信息
Catana Brown, PhD, OTR/L, FAOTA, is Professor, Midwestern University-Glendale, Glendale, AZ;
Lydia C. Geiszler, MOT, OTR/L, is Occupational Therapist, Mayo Clinic Hospital, Saint Mary's Campus, Rochester, MN.
出版信息
Am J Occup Ther. 2018 Sep/Oct;72(5):7205190030p1-7205190030p9. doi: 10.5014/ajot.2018.033415.
OBJECTIVE
We examined the effectiveness of weight loss interventions in community-based settings for people with serious mental illness (SMI).
METHOD
Four databases were searched for randomized controlled trials published in 2008 or later that met the criteria for the research question and used weight loss as an outcome measure. Data were extracted, and weight loss was analyzed using a meta-analysis. Similarities and differences in interventions were analyzed qualitatively.
RESULTS
Seventeen studies and a total of 1,874 participants with various diagnoses of SMI were included in the meta-analysis. The various lifestyle-focused interventions had a significant effect on weight loss with an overall effect size of -0.308 (p < .001).
CONCLUSION
Community-based interventions for people with SMI are effective for weight loss. Occupational therapists can be involved in the provision of weight loss interventions and in the development and study of intervention components that are most effective.
目的
我们研究了社区环境中针对严重精神疾病（SMI）患者的减肥干预措施的有效性。
方法
检索了四个数据库，查找2008年或之后发表的符合研究问题标准且将体重减轻作为结局指标的随机对照试验。提取数据，并使用荟萃分析对体重减轻情况进行分析。对干预措施的异同进行定性分析。
结果
荟萃分析纳入了17项研究，共1874名患有各种SMI诊断的参与者。各种以生活方式为重点的干预措施对体重减轻有显著影响，总体效应大小为-0.308（p < .001）。
结论
针对SMI患者的社区干预措施对减肥有效。职业治疗师可参与提供减肥干预措施以及开发和研究最有效的干预组成部分。
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