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Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe.全球癌症患者可选择的生育力保存方法调查。
JCO Glob Oncol. 2020 Mar 2;6. doi: 10.1200/JGO.2016.008144. eCollection 2020.
2
Repetitive Maturation of Oocytes From Non-Stimulated Xenografted Ovarian Tissue From a Prepubertal Patient Indicating the Independence of Human Ovarian Tissue.来自青春期前患者未受刺激的异种移植卵巢组织的卵母细胞反复成熟，表明人类卵巢组织具有自主性。
Geburtshilfe Frauenheilkd. 2017 Dec;77(12):1304-1311. doi: 10.1055/s-0043-122601. Epub 2017 Dec 18.
3
Fertility Preservation in Pediatric Subspecialties: A Pilot Needs Assessment Beyond Oncology.儿科亚专科中的生育力保存：肿瘤学以外的需求评估试点研究。
J Pediatr. 2018 Mar;194:253-256. doi: 10.1016/j.jpeds.2017.10.072. Epub 2017 Dec 6.
4
Ethics of fertility preservation for prepubertal children: should clinicians offer procedures where efficacy is largely unproven?青春期前儿童生育力保存的伦理问题：临床医生是否应该提供疗效尚未得到充分证实的程序？
J Med Ethics. 2018 Jan;44(1):27-31. doi: 10.1136/medethics-2016-104042. Epub 2017 Oct 30.
5
The testicular transcriptome associated with spermatogonia differentiation initiated by gonadotrophin stimulation in the juvenile rhesus monkey (Macaca mulatta).促性腺激素刺激诱导幼年恒河猴精原细胞分化的睾丸转录组。
Hum Reprod. 2017 Oct 1;32(10):2088-2100. doi: 10.1093/humrep/dex270.
6
Outcomes of immature oocytes collected from ovarian tissue for cryopreservation in adult and prepubertal patients.从成年和青春期前患者卵巢组织中采集用于冷冻保存的未成熟卵母细胞的结果。
Reprod Biomed Online. 2017 Jun;34(6):575-582. doi: 10.1016/j.rbmo.2017.03.007. Epub 2017 Mar 20.
7
The positive effect of a dedicated adolescent and young adult fertility program on the rates of documentation of therapy-associated infertility risk and fertility preservation options.一项专门针对青少年和青年成人的生育计划对治疗相关不孕风险记录率和生育力保存选择的积极影响。
Support Care Cancer. 2017 Jun;25(6):1915-1922. doi: 10.1007/s00520-017-3597-8. Epub 2017 Feb 2.
8
86 successful births and 9 ongoing pregnancies worldwide in women transplanted with frozen-thawed ovarian tissue: focus on birth and perinatal outcome in 40 of these children.全球范围内，接受冻融卵巢组织移植的女性中有86例成功分娩，9例仍在妊娠：重点关注其中40名儿童的出生及围产期结局。
J Assist Reprod Genet. 2017 Mar;34(3):325-336. doi: 10.1007/s10815-016-0843-9. Epub 2016 Dec 27.
9
Preserved seminiferous tubule integrity with spermatogonial survival and induction of Sertoli and Leydig cell maturation after long-term organotypic culture of prepubertal human testicular tissue.青春期前人类睾丸组织长期器官型培养后，生精小管完整性得以保留，精原细胞存活，支持细胞和间质细胞成熟得以诱导。
Hum Reprod. 2017 Jan;32(1):32-45. doi: 10.1093/humrep/dew300. Epub 2016 Dec 6.
10
Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions.在小鼠精原干细胞培养条件下，人类精原干细胞在体外显示出有限的增殖能力。
Fertil Steril. 2016 Nov;106(6):1539-1549.e8. doi: 10.1016/j.fertnstert.2016.07.1065. Epub 2016 Aug 1.

儿科肿瘤生育力保护的现状与未来方向：一篇综述

Current standing and future directions in pediatric oncofertility: a narrative review.

作者信息

Lau Glen A, Schaeffer Anthony J

机构信息

Division of Urology, University of Utah, Salt Lake City, UT, USA.

出版信息

Transl Androl Urol. 2018 Jul;7(Suppl 3):S276-S282. doi: 10.21037/tau.2018.05.04.

DOI:10.21037/tau.2018.05.04
PMID:30159233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6087837/
Abstract

In this narrative review, we discuss the epidemiology and pathophysiology of infertility in childhood and adolescent cancer. We also review the current guidelines and ethical issues related to pediatric oncofertility. Finally, we present recent advances in basic science and translational research in pediatric fertility preservation (FP).

摘要

在这篇叙述性综述中，我们讨论了儿童期和青少年期癌症患者不孕不育的流行病学和病理生理学。我们还回顾了与儿科肿瘤生育力保护相关的现行指南和伦理问题。最后，我们介绍了儿科生育力保存（FP）基础科学和转化研究的最新进展。