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1 型强直性肌营养不良症患者的改良动态步态指数和稳定性极限。

Modified dynamic gait index and limits of stability in myotonic dystrophy type 1.

机构信息

Department of Physical Therapy, University of Saint Augustine Health Sciences, 1 University Boulevard, Room D129, Saint Augustine, Florida, 32086, USA.

Department of Neurology, University of Utah, Salt Lake City, Utah, USA.

出版信息

Muscle Nerve. 2018 Nov;58(5):694-699. doi: 10.1002/mus.26331. Epub 2018 Sep 23.

Abstract

INTRODUCTION

The purpose of this study was to describe and compare the performance of balance and walking tests in relation to self-reported fall history in adults with myotonic dystrophy type 1 (DM1).

METHODS

Twenty-two (13 male) participants with DM1 completed, a 6-month fall history questionnaire, the modified Dynamic Gait Index (mDGI), limits of stability (LoS) testing, and 10-m walking tests.

RESULTS

Mean (SD) falls in 6 months was 3.7 (3.1), and 19 (86%) participants reported at least 1 fall. Significant differences in mDGI scores (P = 0.006) and 10-m fast walking gait velocity (P = 0.02) were found between those who had been classified as "fallers" and those who had been classified as "nonfallers." Significant correlations were found between mDGI scores and 10-m walking time.

DISCUSSION

Falls are common in DM1, and the mDGI may have potential to distinguish fallers from nonfallers, whereas the LoS failed to detect such impairment. Future studies should further explore use of the mDGI in DM1. Muscle Nerve 58: 694-699, 2018.

摘要

简介

本研究的目的是描述和比较与肌强直性营养不良 1 型(DM1)成人自述跌倒史相关的平衡和行走测试的表现。

方法

22 名(13 名男性)DM1 参与者完成了 6 个月的跌倒史问卷、改良动态步态指数(mDGI)、稳定性极限(LoS)测试和 10 米行走测试。

结果

6 个月的平均(SD)跌倒次数为 3.7(3.1),19 名(86%)参与者报告至少有 1 次跌倒。在被归类为“跌倒者”和被归类为“非跌倒者”之间,mDGI 评分(P=0.006)和 10 米快速行走步态速度(P=0.02)存在显著差异。mDGI 评分与 10 米行走时间之间存在显著相关性。

讨论

跌倒在 DM1 中很常见,mDGI 可能有潜力区分跌倒者和非跌倒者,而 LoS 未能检测到这种损伤。未来的研究应进一步探索 mDGI 在 DM1 中的应用。肌肉神经 58:694-699,2018.

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