Kamoun Anis, Hammouda Omar, Yahia Abdelmoneem, Dhari Oussema, Ksentini Houcem, Driss Tarak, Souissi Nizar, Elleuch Mohamed Habib
J Aging Phys Act. 2019 Jun 1;27(3):316-324. doi: 10.1123/japa.2018-0107. Epub 2019 Feb 11.
The present study aimed to investigate the effect of acute nocturnal melatonin (MEL) ingestion on sleep quality, cognitive performance, and postural balance in older adults. A total of 12 older men (58 ± 5.74 years) volunteered to participate in this study. The experimental protocol consisted in two testing sessions after nocturnal MEL (10 mg) or placebo ingestion the night before the tests. During each session, sleep quality tests, cognitive tests, and postural balance protocol were conducted. Static and dynamic postural control was assessed using a force platform. Most of the sleep parameters have been improved following nocturnal MEL ingestion without any effect on cognitive performance. Likewise, measurements related to the center of pressure (CoP) have been significantly decreased with MEL compared with placebo. In conclusion, postural control has been improved the morning following nocturnal MEL ingestion in older adults. This trend could be explained by the potential effect of MEL on sleep quality and cerebellum.
本研究旨在探讨老年人夜间急性摄入褪黑素（MEL）对睡眠质量、认知能力和姿势平衡的影响。共有12名老年男性（58±5.74岁）自愿参与本研究。实验方案包括在测试前一晚夜间摄入MEL（10毫克）或安慰剂后进行两次测试。在每次测试期间，进行睡眠质量测试、认知测试和姿势平衡方案。使用测力平台评估静态和动态姿势控制。夜间摄入MEL后，大多数睡眠参数得到改善，对认知能力没有任何影响。同样，与安慰剂相比，MEL使与压力中心（CoP）相关的测量值显著降低。总之，老年人夜间摄入MEL后，次日早晨的姿势控制得到改善。这种趋势可能是由于MEL对睡眠质量和小脑的潜在影响所致。
