小脑和下丘中苯二氮䓬受体的比较。
Comparison of benzodiazepine receptors in cerebellum and inferior colliculus.
作者信息
Sieghart W
出版信息
J Neurochem. 1986 Sep;47(3):920-3. doi: 10.1111/j.1471-4159.1986.tb00698.x.
Abstract
Reversible and irreversible binding of [3H]flunitrazepam was investigated in membranes from cerebellum and inferior colliculus of young and adult rats. Results indicate that in adult animals predominantly BZ1 receptors are enriched in both brain regions. In the brains of newborn animals, however, additional benzodiazepine receptor subtypes seem to exist in cerebellum as well as in inferior colliculus.
摘要
研究了[3H]氟硝西泮在幼年和成年大鼠小脑及下丘脑中的可逆和不可逆结合。结果表明，在成年动物中，BZ1受体主要在这两个脑区富集。然而，在新生动物的大脑中，小脑和下丘脑中似乎还存在其他苯二氮䓬受体亚型。
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