Gorbachev V V, Pristrom M S
Kardiologiia. 1986 May;26(5):30-3.
Blood ACTH, cortisol and lipid levels, as well as complamin effects thereon, were studied in 116 elderly and old coronary patients. Changes of lipid metabolism were not identical in coronary patients of different age. They were particularly unfavorable in old age. ACTH and cortisol levels and the ACTH/cortisol ratio change with age, and the highest hypercortisolemia is found in old age. Complamin regulates lipid metabolism and blood ACTH and cortisol in coronary patients of advanced age. The ACTH/cortisol ratio is however unaffected by treatment and remains stable in all age groups.
对116例老年和高龄冠心病患者的血促肾上腺皮质激素(ACTH)、皮质醇和血脂水平及其相互作用进行了研究。不同年龄的冠心病患者脂质代谢变化不尽相同。在高龄患者中这些变化尤其不利。ACTH和皮质醇水平以及ACTH/皮质醇比值随年龄变化,高龄患者中皮质醇血症最为严重。Complamin可调节高龄冠心病患者的脂质代谢以及血ACTH和皮质醇水平。然而,ACTH/皮质醇比值不受治疗影响,在所有年龄组中均保持稳定。