Pomerantsev V P, Ivanova N A, Zadionchenko V S, Vertkin A L, Martynov A I
Kardiologiia. 1978 Mar;18(3):36-43.
The results of ksavin treatment of 90 patients suffering from ischemic heart disease are discussed. Ksavin was given in a daily dose of 450-1,200 mg for 3 weeks. The clinical efficacy of the treatment was correlated with the risk factors and the indices of the ECG, centra hemodynamics and spiroergometry. The effect was good in 55% of the patients and satisfactory in 30%. No effect was produced in 15% of the patients. The best results were observed in younger patients with disease of short duration and no concomitant arterial hypertension. A favourable effect of ksavin on lipid metabolism and blood coagulation was noted. The study showed ksavin to be an effective measure in the treatment of ischemic heart disease.
讨论了对90例缺血性心脏病患者使用克沙文治疗的结果。克沙文的日剂量为450 - 1200毫克,疗程为3周。治疗的临床疗效与危险因素以及心电图、中心血流动力学和运动心肺功能测定指标相关。55%的患者效果良好,30%的患者效果令人满意。15%的患者没有效果。在病程短且无合并动脉高血压的年轻患者中观察到最佳效果。注意到克沙文对脂质代谢和血液凝固有有利作用。该研究表明克沙文是治疗缺血性心脏病的有效措施。