Port Matthias, Abend Michael
Bundeswehr Institute of Radiobiology Affiliated to the University Ulm, Munich, Germany.
Radiat Prot Dosimetry. 2018 Dec 1;182(1):90-92. doi: 10.1093/rpd/ncy141.
Novel treatment regimens for therapy of the acute radiation syndrome (ARS) were developed over the last years. Their application relies on an early and high-throughput diagnosis. Based on the database SEARCH a new scientific triage tool (called H-module) was developed for early prediction of the later developing ARS. Based on peripheral blood cell counts measured within the first three days after a radiation exposure a prediction of the H-ARS severity (as well as therapeutic recommendations) can be performed with this tool. The H-module was tested within two table top exercises. Contributors were either radiation experts or radiobiology students and the required patient data were generated from real case histories. The H-module proved to be an easy to train and easy to use precise and promising new tool to assist and guide the treating physician in a large-scale radiation scenario. An introduction into this new tool and other diagnostic tools will be provided in the context of a NATO-teaching class in October/November 2019 in Paris.
在过去几年中，针对急性放射综合征（ARS）开发了新的治疗方案。这些方案的应用依赖于早期和高通量诊断。基于数据库SEARCH，开发了一种新的科学分诊工具（称为H模块），用于早期预测后期发生的ARS。根据辐射暴露后前三天内测量的外周血细胞计数，使用该工具可以预测H-ARS的严重程度（以及治疗建议）。H模块在两次桌面演练中进行了测试。参与者要么是放射专家，要么是放射生物学学生，所需的患者数据来自真实病例记录。H模块被证明是一种易于培训、易于使用、精确且有前景的新工具，可在大规模辐射场景中协助和指导治疗医生。2019年10月/11月在巴黎举行的北约教学课程将介绍这种新工具和其他诊断工具。
