铜催化末端炔烃的偕二官能团化反应，通过将磺酰腙裂解成两部分。
Copper-Catalyzed Geminal Difunctionalization of Terminal Alkynes by Splitting Sulfonyl Hydrazones into Two Parts.
机构信息
Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry & Center for Excellence in Molecular Synthesis of Chinese Academy of Sciences , Collaborative Innovation Center of Suzhou Nano Science and Technology & School of Chemistry and Materials Science in University of Science and Technology of China , Hefei , Anhui 230026 , P. R. China.
出版信息
Org Lett. 2018 Sep 21;20(18):5592-5596. doi: 10.1021/acs.orglett.8b02268. Epub 2018 Aug 31.
A copper(I)-catalyzed geminal difunctionalization of terminal alkynes was developed via a carbene migratory insertion and an addition of a sulfonyl anion to the triple bond at the same time under mild reaction conditions, providing a variety of vinyl sulfones with good yields and excellent stereoselectivities.
发展了一种铜（I）催化的末端炔烃的偕二官能团化反应，通过卡宾迁移插入和磺酰阴离子同时加成到叁键上，在温和的反应条件下，以良好的收率和优异的立体选择性得到了多种乙烯基砜。
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