包皮环切术可降低男性人乳头瘤病毒感染的发生率。

[Circumcision reduces the incidence of human papillomavirus infection in men].

作者信息

Huang Liang-Liang, Deng Jun-Hong, Shi Hua, Ou-Yang Bin, Liu Jian-Ming, Lin Zi-Bin, Xie Jing-Xuan, Wei Yan-Ni, Huang Xiao-Hui

机构信息

Department of Andrology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510180, China.

出版信息

Zhonghua Nan Ke Xue. 2018 Apr;24(4):327-330.

PMID:30168952

Abstract

OBJECTIVE

To investigate the association of circumcision with the incidence of human papillomavirus (HPV) infection in men.

METHODS

We collected the samples from the surface of the coronal sulcus, glans penis, penile shaft and scrotum of 351 males examined for HPV infection in our hospital from January 2016 to August 2017, of whom 118 had received circumcision while the other 233 had not. We compared the incidence rate of HPV infection between the circumcision and non-circumcision groups and analyzed the association of the age of circumcision with the incidence of HPV infection.

RESULTS

HPV infection was found in 135 (38.46%) of the males, 29 (24.58%) in the circumcision group and 106 (45.49%) in the non-circumcision group, significantly lower in the former than in the latter (χ² = 14.48, P < 0.01). The incidence rate of HPV infection was also remarkably lower in the males circumcised at ≤17 years (13.16% ［5/38］) than in those circumcised at >17 years of age (30.0% ［24/80］) (χ² = 3.942, P = 0.047).

CONCLUSIONS

Male circumcision helps reduce the incidence rate of HPV infection in men and earlier surgery may achieve even better effect.

摘要

目的

探讨包皮环切术与男性人乳头瘤病毒（HPV）感染发生率之间的关联。

方法

收集2016年1月至2017年8月在我院接受HPV感染检测的351名男性冠状沟、龟头、阴茎体和阴囊表面的样本，其中118人接受了包皮环切术，另外233人未接受。比较包皮环切术组和未包皮环切术组HPV感染的发生率，并分析包皮环切术年龄与HPV感染发生率之间的关联。

结果

135名（38.46%）男性检测出HPV感染，其中包皮环切术组29名（24.58%），未包皮环切术组106名（45.49%），前者显著低于后者（χ² = 14.48，P < 0.01）。≤17岁接受包皮环切术的男性HPV感染发生率（13.16% ［5/38］）也显著低于>17岁接受包皮环切术的男性（30.0% ［24/80］）（χ² = 3.942，P = 0.047）。