Division of Cardiac Surgery.
Curr Opin Cardiol. 2018 Nov;33(6):633-637. doi: 10.1097/HCO.0000000000000566.
In 2013, heart failure with recovered ejection fraction (HFrecEF) was introduced as a new heart failure phenotype. This review provides an overview of HFrecEF and the comparative effects of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) on left ventricular ejection fraction (LVEF) recovery in patients with ischemic cardiomyopathy.
There has been emerging data indicating that LV functional recovery is possible and HFrecEF is associated with improved survival and better quality of life. CABG may be associated with larger improvement in LVEF when compared with PCI. However, there is significant paucity of studies, which directly compare the impact of PCI and CABG on LVEF recovery in the setting of ischemic cardiomyopathy.
LVEF recovery is emerging as an important outcome with demonstrated survival and quality-of-life benefits. Future randomized clinical trials comparing the impact of contemporary PCI and CABG on LVEF recovery are needed in patients with ischemic cardiomyopathy.
2013 年,射血分数恢复的心力衰竭(HFrecEF)被引入一种新的心力衰竭表型。本综述概述了 HFrecEF 以及经皮冠状动脉介入治疗(PCI)和冠状动脉旁路移植术(CABG)对缺血性心肌病患者左心室射血分数(LVEF)恢复的比较效果。
越来越多的数据表明,LV 功能恢复是可能的,HFrecEF 与改善的生存和更好的生活质量相关。与 PCI 相比,CABG 可能与 LVEF 的更大改善相关。然而,直接比较 PCI 和 CABG 对缺血性心肌病患者 LVEF 恢复影响的研究非常有限。
LVEF 恢复作为一个重要的结果出现,具有已证明的生存和生活质量获益。需要在缺血性心肌病患者中进行比较当代 PCI 和 CABG 对 LVEF 恢复影响的未来随机临床试验。