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美国一个主要大都市地区通用泌尿科药物零售价格的可变性。

Variability of Retail Pricing of Generic Urologic Medications in a Major US Metropolitan Area.

作者信息

Xu Perry J, Barnes Justin M, Choe Emily M, Syed Johar R, Siddiqui Sameer A

机构信息

Saint Louis University School of Medicine, Saint Louis, MO.

Saint Louis University School of Medicine, Saint Louis, MO.

出版信息

Urology. 2019 Mar;125:29-33. doi: 10.1016/j.urology.2018.07.045. Epub 2018 Aug 28.

DOI:10.1016/j.urology.2018.07.045
PMID:30170089
Abstract

OBJECTIVE

To investigate retail pricing for generic urologic medications in the St. Louis area as a function of pharmacy type, zip-code, and median income.

MATERIALS AND METHODS

Pharmacies spanning 51 zip-codes were identified. From May-June 2017, pharmacies were inquired regarding cost, without insurance, for 30- and 90-tablet prices for finasteride 5 mg, tamsulosin 0.4 mg, oxybutynin 5 mg, and oxybutynin extended release (ER) 5 mg and 10 mg. Median income was determined using US census data. K-means clustering defined groupings based on zip-code, median income, and a combination of the two. Pricing between groups and pharmacy type was compared using Kruskal-Wallis and Wilcoxon rank-sum tests. Associations between pricing and median income were tested using Spearman's rho.

RESULTS

152 chain and 16 independent pharmacies provided data. Retail pricing for generic urologic medications did not vary as a function of zip-code, median income, or a combination of the two. There was a significant difference in the pricing of tamsulosin 0.4 mg, and oxybutynin ER 5 mg and 10 mg based on pharmacy type, where independent pharmacies have significantly lower prices compared to chain (P = .00-.00003).

CONCLUSION

Pricing for generic urologic medications demonstrated wide variability at the retail pharmacy level. Compared to chain, independent pharmacies have significantly lower pricing for tamsulosin 0.4 mg, and oxybutynin ER 5 mg and 10 mg. Pharmacy zip-code, median income, and a combination of the two did not correlate with pricing.

摘要

目的

研究圣路易斯地区普通泌尿科药物的零售价格与药房类型、邮政编码和收入中位数之间的关系。

材料与方法

确定了覆盖51个邮政编码区域的药房。在2017年5月至6月期间,询问了各药房非医保情况下非那雄胺5毫克、坦索罗辛0.4毫克、奥昔布宁5毫克以及奥昔布宁缓释片(ER)5毫克和10毫克的30片装和90片装价格。使用美国人口普查数据确定收入中位数。采用K均值聚类法根据邮政编码、收入中位数以及两者的组合进行分组。使用Kruskal-Wallis检验和Wilcoxon秩和检验比较不同组和药房类型之间的价格。使用Spearman秩相关系数检验价格与收入中位数之间的关联。

结果

152家连锁药房和16家独立药房提供了数据。普通泌尿科药物的零售价格不会因邮政编码、收入中位数或两者的组合而有所不同。基于药房类型,坦索罗辛0.4毫克、奥昔布宁ER 5毫克和10毫克的价格存在显著差异,独立药房的价格明显低于连锁药房(P = 0.00 - 0.00003)。

结论

普通泌尿科药物在零售药房层面的价格差异很大。与连锁药房相比,独立药房的坦索罗辛0.4毫克、奥昔布宁ER 5毫克和10毫克的价格明显更低。药房的邮政编码、收入中位数以及两者的组合与价格均无关联。

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