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德国社区药房急性腹泻的药物配给、额外治疗建议及定价实践:一项模拟患者研究

Medication dispensing, additional therapeutic recommendations, and pricing practices for acute diarrhoea by community pharmacies in Germany: a simulated patient study.

作者信息

Langer Bernhard, Kunow Christian

机构信息

Department of Health, Nursing, Management, University of Applied Sciences Neubrandenburg. Neubrandenburg (Germany).

Research Associate. Department of Health, Nursing, Management, University of Applied Sciences Neubrandenburg. Neubrandenburg (Germany).

出版信息

Pharm Pract (Granada). 2019 Jul-Sep;17(3):1579. doi: 10.18549/PharmPract.2019.3.1579. Epub 2019 Sep 14.

Abstract

BACKGROUND

In Germany over-the-counter medications (OTC) - which since 2004 are no longer subject to binding prices - can only be purchased in pharmacies. Pharmacy owners and their staff therefore have a special responsibility when dispensing, advising on and setting the prices of medications.

OBJECTIVE

The aim of this study was to assess medication dispensing, additional therapeutic recommendations and pricing practices for acute diarrhoea in adults and to evaluate the role of the patient's approach (symptom-based versus medication-based request) in determining the outcome of these aspects.

METHODS

A cross-sectional study was conducted from 1 May to 31 July 2017 in all 21 community pharmacies in a medium-sized German city. Symptom-based and medication-based scenarios related to self-medication of acute diarrhoea were developed and used by five simulated patients (SPs) in all of the pharmacies (a total of 84 visits). Differentiating between the different test scenarios in terms of the commercial and active ingredient names and also the prices of the medications dispensed, the SPs recorded on collection forms whether the scenario involved generic products or original preparations as well as whether recommendations were made during the test purchases regarding an additional intake of fluids.

RESULTS

In each of the 84 test purchases one preparation was dispensed. However, a preparation for oral rehydration was not sold in a single test purchase. On the other hand, in 74/84 (88%) of test purchases, medications with the active ingredient loperamide were dispensed. In only 35/84 (42%) of test purchases, the patient was also recommended to ensure an 'adequate intake of fluids' in addition to being dispensed a medication. In symptom-based scenarios significantly more expensive medications were dispensed compared to the medication-based scenarios (Wilcoxon signed rank test: z = -4.784, p < 0.001, r = 0.738). Also within the different scenarios there were enormous price differences identified - for example, in the medication-based scenarios, even for comparable loperamide generics the cheapest preparation cost EUR 1.99 and the most expensive preparation cost EUR 4.53.

CONCLUSIONS

Oral rehydration was not dispensed and only occasionally was an adequate intake of fluids recommended. There were also enormous price differences both between and within the scenarios investigated.

摘要

背景

在德国,非处方药(自2004年起不再受固定价格限制)只能在药店购买。因此,药店店主及其员工在配药、提供用药建议和定价方面负有特殊责任。

目的

本研究旨在评估成人急性腹泻的配药情况、额外的治疗建议和定价做法,并评估患者的询问方式(基于症状与基于药物的询问)在决定这些方面结果中的作用。

方法

2017年5月1日至7月31日,在德国一个中等城市的所有21家社区药店进行了一项横断面研究。由五名模拟患者(SP)在所有药店制定并使用与急性腹泻自我药疗相关的基于症状和基于药物的场景(共84次就诊)。根据商品名、活性成分名称以及所配药物的价格区分不同的测试场景,SP在收集表上记录该场景涉及的是仿制药还是原研制剂,以及在测试购买过程中是否就额外补充液体给出了建议。

结果

在84次测试购买中,每次都配了一种制剂。然而,在任何一次测试购买中都没有售出口服补液制剂。另一方面,在74/84(88%)的测试购买中,配了活性成分是洛哌丁胺的药物。在仅35/84(42%)的测试购买中,除了给患者配药外,还建议患者确保“充足的液体摄入”。与基于药物的场景相比,在基于症状的场景中配的药明显更贵(Wilcoxon符号秩检验:z = -4.784,p < 0.001,r = 0.738)。而且在不同场景中也发现了巨大的价格差异——例如,在基于药物的场景中,即使是可比的洛哌丁胺仿制药,最便宜的制剂售价为1.99欧元,最贵的制剂售价为4.53欧元。

结论

未配口服补液制剂,仅偶尔建议充足的液体摄入。在所调查的场景之间和场景内部也存在巨大的价格差异。

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