一项针对华盛顿特区与男性发生性行为的年轻黑人男性中增加 HIV 暴露前预防措施的接受率的文化定制咨询干预的随机对照试点研究。
A Randomized Controlled Pilot Study of a Culturally-Tailored Counseling Intervention to Increase Uptake of HIV Pre-exposure Prophylaxis Among Young Black Men Who Have Sex with Men in Washington, DC.
机构信息
Division of Infectious Disease, Department of Medicine, George Washington University Medical Faculty Associates, 2150 Pennsylvania Avenue, NW, Suite 8-436, Washington, DC, 20037, USA.
Department of Epidemiology and Biostatistics, Milken Institute School of Public Health at the George Washington University, Washington, DC, 20052, USA.
出版信息
AIDS Behav. 2019 Jan;23(1):105-115. doi: 10.1007/s10461-018-2264-5.
Abstract
Daily emtricitabine/tenofovor is effective at preventing HIV acquisition and is approved for HIV pre-exposure prophylaxis (PrEP). Blacks in the United States have a disproportionately high rate of HIV, and uptake of PrEP has been very low in this population. We conducted a pilot study in a high-prevalence city to test whether a culturally-tailored counseling center for young Black men who have sex with men (BMSM) positively impacted their access and uptake of PrEP. 50 young BMSM were randomized to either a PrEP counseling center group or a control group, and were then encouraged to obtain PrEP from a PrEP provider. At the end of 3 month study, six participants in the intervention group compared with none in the control group had initiated PrEP (p = 0.02). This pilot study demonstrates that a culturally-tailored counseling center might be an effective at increasing the uptake of PrEP in young BMSM.
摘要
每日服用恩曲他滨/替诺福韦酯可有效预防 HIV 感染，且已被批准用于 HIV 暴露前预防（PrEP）。美国的黑人 HIV 感染率极高，而该人群对 PrEP 的接受度非常低。我们在一个高感染率的城市开展了一项试点研究，以测试为与男性发生性行为的年轻黑人男性（BMSM）设立的文化适应型咨询中心是否能积极影响他们获得和使用 PrEP 的机会。将 50 名年轻的 BMSM 随机分配到 PrEP 咨询中心组或对照组，然后鼓励他们从 PrEP 提供者处获得 PrEP。在 3 个月的研究结束时，干预组中有 6 名参与者开始使用 PrEP，而对照组中无一例（p=0.02）。这项试点研究表明，文化适应型咨询中心可能会有效提高年轻 BMSM 使用 PrEP 的机会。
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