Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.
Department of Medicine, JIPMER, Puducherry, India.
Adv Ther. 2018 Oct;35(10):1519-1534. doi: 10.1007/s12325-018-0744-7. Epub 2018 Aug 31.
Hypothyroidism presents a large epidemiological burden in India. As a result of subtle and nonspecific clinical symptoms and signs, the condition often goes undiagnosed and is not adequately treated when it is detected. There is heterogeneity in the diagnostic and treatment approaches to hypothyroidism. As a result of the physiological changes in thyroid hormones with age and illness, it is important to tailor the diagnosis and management of this condition in specific populations including pregnant women, infants, children, geriatric patients, and those with comorbid conditions. Enhanced understanding and education of physicians and patients can help to improve the outcomes of treatment in hypothyroidism which should be focused on patient-centered care. Policies and reforms should be crafted and implemented at the national level to curb public health challenges of hypothyroidism. This publication summarizes the recommendations of a national advisory board meeting to identify and bridge the gaps in understanding of the diagnosis and treatment of hypothyroidism in India. As a complement to clinical judgment, these recommendations will foster the diagnosis and management of hypothyroidism in the community and clinics for the benefit of the patients.
Merck Ltd, India.
甲状腺功能减退症在印度具有较大的流行病学负担。由于其临床症状和体征较为隐匿且非特异性，因此该疾病常被漏诊，即使被发现也未能得到充分治疗。甲状腺功能减退症的诊断和治疗方法存在差异。由于甲状腺激素会随年龄和疾病而发生生理性变化，因此针对包括孕妇、婴儿、儿童、老年患者以及合并症患者在内的特定人群，调整该疾病的诊断和管理方法非常重要。提高医生和患者的认识和教育水平有助于改善甲状腺功能减退症的治疗效果，应重点关注以患者为中心的治疗。应在国家层面制定和实施政策和改革措施，以遏制甲状腺功能减退症这一公共卫生挑战。本出版物总结了一次国家咨询委员会会议的建议，以确定和弥合印度甲状腺功能减退症诊断和治疗方面的认识差距。这些建议将作为临床判断的补充，促进社区和诊所对甲状腺功能减退症的诊断和管理，从而使患者受益。
印度默克有限公司。
