Kurihara M, Anzai K, Kumagai K, Yasui A, Tomie E, Kawachi M, Hanada E, Sugimoto H, Saitoh T, Tokuhisa Y
Gan To Kagaku Ryoho. 1986 Aug;13(8):2495-504.
First, we presented an actual diagnostic situation in nowadays for gastric cancer of Borrmann 4, which is virtually the same as scirrhous gastric cancer. Among 12 patients treated by the author, all of whom were discovered late, only 3 underwent surgery. In fact, with inoperable cases in Borrmann 4, even those endoscopically found to show insufficient stretching of the gastric wall, thickening and tortuosity of folds, uneven gastric mucosa, redness and white coating, there may be negative in gastric biopsy. However, the significance of an endoscopic examination for diagnosis of scirrhous cancer is in obtaining proof of the carcinoma (especially when still operable) by gastric biopsy. Thus, one must strive not to overlook slight redness, white coating which means small erosions, but to go over gastric biopsy again and again. Next, with carcinoma presenting a leather bottle (linitis plastica type) of the stomach itself, the II c portion of the stomach consisted of fundic glands (undifferentiated carcinoma) shall become the primary focus supporting Nakamura's theory. One case of diffuse invasive cancer, mistakenly diagnosed as a II c case, and two cases of regional type, one similar to II c and the other a Borrmann 2 carcinoma of advanced carcinoma showing strongly fibrous scirrhous tendency toward infiltration, were jointly monitored.
首先,我们呈现了当下Borrmann 4型胃癌的实际诊断情况,其实际上与硬癌性胃癌相同。在作者治疗的12例患者中,所有患者均发现较晚,只有3例接受了手术。事实上,对于Borrmann 4型无法手术的病例,即使在内镜检查中发现胃壁伸展不足、皱襞增厚和迂曲、胃黏膜不均匀、发红和有白色覆盖物,胃活检也可能为阴性。然而,内镜检查对硬癌诊断的意义在于通过胃活检获得癌症证据(尤其是在仍可手术时)。因此,必须努力不忽视轻微发红、意味着小糜烂的白色覆盖物,而是要反复进行胃活检。接下来,对于呈现胃自身皮革样改变(皮革胃型)的癌症,胃的II c部分由胃底腺(未分化癌)组成应成为支持中村理论的主要病灶。对1例被误诊为II c病例的弥漫浸润性癌以及2例区域型病例进行了联合监测,其中1例类似于II c,另1例为晚期癌的Borrmann 2型癌,显示出强烈纤维化硬癌倾向浸润。