肌醇磷脂：生物活性的立体化学视角 - Suppr

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超能文献

The inositol phospholipids: a stereochemical view of biological activity.

作者信息

Parthasarathy R, Eisenberg F

出版信息

Biochem J. 1986 Apr 15;235(2):313-22. doi: 10.1042/bj2350313.

DOI:10.1042/bj2350313

PMID:3017301

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1146689/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b0/1146689/dcf514ac1d82/biochemj00281-0010-a.jpg

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The inositol phospholipids: a stereochemical view of biological activity.肌醇磷脂：生物活性的立体化学视角

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Toward a crystal-clear view of lithium's site of action.迈向对锂作用位点的清晰认识。

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Changes in the 31P-NMR spectra of cats receiving lithium chloride systemically.全身接受氯化锂的猫的31P-NMR光谱变化。

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Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers.双膦酸盐肌醇单磷酸酶抑制剂L-690,330的前体药物L-690,488对磷脂酰肌醇循环标志物的影响。

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Inhibitors of inositol monophosphatase.肌醇单磷酸酶抑制剂

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The dephosphorylation of inositol 1,4-bisphosphate to inositol in liver and brain involves two distinct Li+-sensitive enzymes and proceeds via inositol 4-phosphate.肝脏和大脑中肌醇1,4 - 二磷酸脱磷酸化为肌醇的过程涉及两种不同的锂敏感酶，并通过肌醇4 - 磷酸进行。

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Lithium and myo-inositol homeostasis.锂与肌醇稳态

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Beryllium competitively inhibits brain myo-inositol monophosphatase, but unlike lithium does not enhance agonist-induced inositol phosphate accumulation.铍竞争性抑制脑肌醇单磷酸酶，但与锂不同的是，它不会增强激动剂诱导的肌醇磷酸积累。

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Evidence that inositol 1-phosphate in brain of lithium-treated rats results mainly from phosphatidylinositol metabolism.锂处理大鼠大脑中肌醇 1 - 磷酸主要源于磷脂酰肌醇代谢的证据。

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Disruption of phosphoinositide signalling by lithium.锂对磷酸肌醇信号传导的干扰。

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Analysis of Inositol Phosphates, Diphosphoinositol Phosphates, and Their Analogs by HPLC on an Acid-Compatible Stationary Phase with Detection by Complexation with Ferric Ion.在酸性兼容固定相上通过高效液相色谱法分析肌醇磷酸、二磷酸肌醇磷酸及其类似物，并通过与铁离子络合进行检测。

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Front Pharmacol. 2019 Oct 11;10:1172. doi: 10.3389/fphar.2019.01172. eCollection 2019.

Rat brain myo-inositol 3-phosphate synthase is a phosphoprotein.鼠脑肌醇-3-磷酸合酶是一种磷酸化蛋白。

Mol Cell Biochem. 2013 Jun;378(1-2):83-9. doi: 10.1007/s11010-013-1597-7. Epub 2013 Mar 16.

Phosphoinositide signaling plays a key role in cytokinesis.磷酸肌醇信号传导在胞质分裂中起关键作用。

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Confirmation of the identities of inositol 1,3,4-trisphosphate and inositol 1,3,4,5-tetrakisphosphate by the use of one-dimensional and two-dimensional n.m.r. spectroscopy.通过一维和二维核磁共振光谱法确认肌醇1,3,4 - 三磷酸酯和肌醇1,3,4,5 - 四磷酸酯的身份。

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L-myo-inositol 1,4,5,6-tetrakisphosphate is present in both mammalian and avian cells.L-肌醇1,4,5,6-四磷酸存在于哺乳动物和鸟类细胞中。

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Effect of phorbol-12-myristate-13-acetate (PMA) on the fine structure of Trypanosoma cruzi and its interaction with activated and resident macrophages.佛波醇-12-肉豆蔻酸酯-13-乙酸酯（PMA）对克氏锥虫精细结构及其与活化巨噬细胞和常驻巨噬细胞相互作用的影响。

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Numbering of atoms in myo-inositol. Recommendations 1988. Nomenclature Committee of the International Union of Biochemistry.肌醇中原子的编号。1988年建议。国际生物化学联盟命名委员会

Biochem J. 1989 Feb 15;258(1):1-2.

本文引用的文献

Enantiomeric Form of myo-Inositol-1-Phosphate Produced by myo-Inositol-1-Phosphate Synthase and myo-Inositol Kinase in Higher Plants.高等植物中肌醇-1-磷酸合酶和肌醇激酶产生的肌醇-1-磷酸对映异构体。

Plant Physiol. 1982 Dec;70(6):1661-3. doi: 10.1104/pp.70.6.1661.

A NONENZYMATIC ILLUSTRATION OF "CITRIC ACID TYPE" ASYMMETRY: THE MESO-CARBON ATOM.“柠檬酸型”不对称性的非酶促示例：内消旋碳原子。

Proc Natl Acad Sci U S A. 1954 Jun;40(6):499-508. doi: 10.1073/pnas.40.6.499.

The enzymatic synthesis of inositol monophosphatide.肌醇单磷酸酯的酶促合成。

J Biol Chem. 1960 May;235:1303-11.

Phosphoinositides. 2. The inositol 1-phosphate structure in liver phosphatidylinositol.磷酸肌醇。2. 肝脏磷脂酰肌醇中的肌醇1-磷酸结构。

Biochem J. 1960 Jun;75(3):501-4. doi: 10.1042/bj0750501.

Stereochemistry of enzymic hydrogen transfer to pyridine nucleotides.酶促氢转移至吡啶核苷酸的立体化学

Biochem Biophys Res Commun. 1962 Nov 27;9:371-5. doi: 10.1016/0006-291x(62)90018-9.

Synthesis of galactosylinositol by extracts from peas.豌豆提取物合成半乳糖基肌醇。

Biochem Biophys Res Commun. 1963 Jul 18;12:121-5. doi: 10.1016/0006-291x(63)90246-8.

Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase.植酸酶使植酸去磷酸化过程中的肌醇多磷酸中间体

Biochemistry. 1962 Jan;1:166-71. doi: 10.1021/bi00907a025.

Biochemical studies on inositol. V. Purification and properties of the enzyme that cleaves inositol to D-glucuronic acid.肌醇的生化研究。V. 将肌醇裂解为D - 葡萄糖醛酸的酶的纯化及性质

J Biol Chem. 1959 Feb;234(2):220-7.

The enzymatic synthesis of inositol phosphatide.肌醇磷脂的酶促合成。

J Biol Chem. 1958 Nov;233(5):1077-83.

L-myo-Inositol-1-phosphate synthase from bovine testis: purification to homogeneity and partial characterization.来自牛睾丸的L-肌醇-1-磷酸合酶：纯化至同质并进行部分特性鉴定。

Biochemistry. 1980 Jul 22;19(15):3623-9. doi: 10.1021/bi00556a031.

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