Mansell Josephine, Gourtsoyannis Yannis, Draz Nehal, Buchanan Ruaridh
Department of Cardiology, Barts Health NHS Trust, London, UK.
Department of Microbiology, North Middlesex University Hospital NHS Trust, London, UK.
BMJ Case Rep. 2018 Sep 1;2018:bcr-2018-225871. doi: 10.1136/bcr-2018-225871.
is an anaerobic gram-positive organism associated with genitourinary infections. Bacteraemia is rare, with only two cases reported in the literature. This case describes an 18-year-old type 1 diabetic, presenting with sepsis and haemoptysis, on a background of poor dental hygiene and recurrent hospital admissions. Blood cultures grew and echocardiogram revealed a large tricuspid valve lesion. Despite medical therapy, symptoms of pulmonary emboli continued and she therefore underwent surgical resection of the lesion. Histopathological findings were of a vegetation; culture of the lesion was negative but 16S ribosomal PCR was positive, detecting 16S rRNA of The patient was treated with 4 weeks of vancomycin and made a good recovery. To our knowledge, this represents the first report of infective endocarditis due to this organism. We also provide a review of the literature, including comparing published drug susceptibility data with consensus breakpoints for antimicrobial agents.
是一种与泌尿生殖系统感染相关的厌氧革兰氏阳性菌。菌血症罕见，文献中仅报道过两例。该病例描述了一名18岁的1型糖尿病患者，因口腔卫生差和反复住院，出现败血症和咯血。血培养生长出[具体细菌名称未给出]，超声心动图显示有一个大的三尖瓣病变。尽管进行了药物治疗，但肺栓塞症状仍持续，因此她接受了病变的手术切除。组织病理学检查发现有赘生物；病变培养为阴性，但16S核糖体PCR呈阳性，检测到[具体细菌名称未给出]的16S rRNA。患者接受了4周的万古霉素治疗，恢复良好。据我们所知，这是该菌引起感染性心内膜炎的首例报告。我们还提供了文献综述，包括将已发表的药敏数据与抗菌药物的共识断点进行比较。
