Niles Denver, Larsen Brett, Balaji Arvind, Delaney Dana, Campos Elizabeth, Bhattarai Bikash, Shoshan Dor, Connell Mary, Ostovar Gholamabbas Amin
1 Maricopa Medical Center, Phoenix, AZ, USA.
2 University of Arizona, Phoenix, AZ, USA.
Clin Pediatr (Phila). 2018 Dec;57(14):1686-1692. doi: 10.1177/0009922818795902. Epub 2018 Sep 3.
We performed a retrospective study to evaluate demographics, clinical course, outcome, and radiological findings of children with respiratory syncytial virus (RSV) infection.
Four hundred patients admitted between October 2013 and May 2016 were enrolled. Clinical and radiographic trends were evaluated for association with severity of RSV presentation. Severity was defined as hospitalization >2 days, pediatric intensive care unit admission, or need for mechanical ventilation.
Common clinical findings included fever (78.5%), coughing (97%), rhinorrhea/congestion (93%), and hypoxia (44.8%). Hypoxia was seen in 64.7% of the severe group compared with 32.0% in the nonsevere group ( P < .001). Airspace opacification was seen in 49.2% of chest X-rays of the severe group compared with 26.4% in the nonsevere group ( P < .001).
Higher incidence of hypoxia or airspace opacification on chest X-ray may be predictors of poorer outcomes for patients with RSV infection.
我们进行了一项回顾性研究，以评估呼吸道合胞病毒（RSV）感染儿童的人口统计学特征、临床病程、结局及影像学表现。
纳入2013年10月至2016年5月期间收治的400例患者。评估临床和影像学趋势与RSV表现严重程度之间的关联。严重程度定义为住院时间>2天、入住儿科重症监护病房或需要机械通气。
常见临床症状包括发热（78.5%）、咳嗽（97%）、流涕/鼻塞（93%）及缺氧（44.8%）。严重组中64.7%出现缺氧，非严重组为32.0%（P<.001）。严重组胸部X线检查中49.2%出现肺野实变，非严重组为26.4%（P<.001）。
胸部X线检查中缺氧或肺野实变发生率较高可能是RSV感染患者预后较差的预测指标。
