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用于皮瓣监测的血糖水平变化测量比值

Ratio of Blood Glucose Level Change Measurement for Flap Monitoring.

作者信息

Karakawa Ryo, Yoshimatsu Hidehiko, Narushima Mitsunaga, Iida Takuya

机构信息

Department of Plastic and Reconstructive Surgery, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

Department of Plastic and Reconstructive Surgery, Mie University Hospital, Mie, Japan.

出版信息

Plast Reconstr Surg Glob Open. 2018 Jul 16;6(7):e1851. doi: 10.1097/GOX.0000000000001851. eCollection 2018 Jul.

Abstract

BACKGROUND

In a setting of flap congestion, early detection and rapid reexploration are important. Some studies described the efficacy of blood glucose measurement for flap monitoring. However, the sensitivity and specificity of this method were not high enough to determine whether reexploration should be done or not. The purpose of this study was to evaluate and establish a method using the ratio of blood glucose level change (RBGC) measurement for detecting venous thrombosis and to propose an algorithm for flap salvage after congestion.

METHODS

Blood glucose level was measured in 36 free tissue transfers over time postoperatively and RBGC was calculated. When flap congestion was suspected, frequent blood glucose measurement and some countermeasures were performed complying with an algorithm. If the venous thrombus was suspected, the reexploration was performed. The RBGCs at the points in time when the venous thrombosis was detected were compared with those at the points in time when the flap demonstrated no venous thrombosis.

RESULTS

Of the 36 flaps, 30 flaps demonstrated no venous thrombosis and 6 flaps demonstrated venous thrombosis. Four flaps demonstrated signs of congestion but improved after the reexploration. The mean RBGCs at the points in time when the venous thrombosis was detected was -7.61 mg/dl h and those at times when the flap demonstrated no venous thrombosis was 0.10 mg/dl h, the former being significantly lower than the latter.

CONCLUSION

Using the flap monitoring method using RBGC measurement, we could salvage some flaps from the congestion due to the venous thrombosis without unnecessary reexploration.

摘要

背景

在皮瓣出现充血的情况下,早期检测和快速再次探查很重要。一些研究描述了血糖测量用于皮瓣监测的效果。然而,该方法的敏感性和特异性不足以确定是否应进行再次探查。本研究的目的是评估并建立一种使用血糖水平变化率(RBGC)测量来检测静脉血栓形成的方法,并提出一种在皮瓣充血后挽救皮瓣的算法。

方法

对36例游离组织移植术后随时间测量血糖水平并计算RBGC。当怀疑皮瓣充血时,按照算法进行频繁的血糖测量并采取一些对策。如果怀疑有静脉血栓,则进行再次探查。将检测到静脉血栓形成时的RBGC与皮瓣未出现静脉血栓形成时的RBGC进行比较。

结果

36例皮瓣中,30例未出现静脉血栓形成,6例出现静脉血栓形成。4例皮瓣出现充血迹象,但再次探查后好转。检测到静脉血栓形成时的平均RBGC为-7.61mg/dl·h,皮瓣未出现静脉血栓形成时的平均RBGC为0.10mg/dl·h,前者显著低于后者。

结论

使用基于RBGC测量的皮瓣监测方法,我们可以在不进行不必要的再次探查的情况下,挽救一些因静脉血栓形成而充血的皮瓣。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8408/6110689/f718df4b4863/gox-6-e1851-g003.jpg

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