Ospina-Cantillo July Andrea, Ramírez-Giraldo Ruth Helena, Castelblanco-Arango Iris Yansa, Cardona Ricardo
Universidad de Antioquia, Grupo de Alergología Clínica y Experimental, Medellín, Colombia.
Rev Alerg Mex. 2018 Jul-Sep;65(3):299-303. doi: 10.29262/ram.v65i3.332.
Frey's syndrome is a group of symptoms that include unilateral sweating with malar region and external ear reddening after eating or drinking some food. It is a lesion of the auriculotemporal nerve that is secondary to surgery, parotid gland infection or facial trauma.
Three children between 4 and two and a half years of age: two girls and one boy. They had self-limiting unilateral erythematous facial macules that reached the external ear, without rash, itching, angioedema and gastrointestinal or respiratory symptoms; its onset was associated with the consumption of acid and some sweet foods. Symptom reproduction of was observed in the path of the auriculotemporal nerve. Their histories included cesarean section delivery owing to cephalopelvic disproportion (case 1), birth by operative vaginal delivery with forceps (case 2) and cesarean delivery owing to preeclampsia (case 3).
Frey's syndrome is often mistaken with food allergy, leading to unnecessary dietary restrictions. Sweating is often absent in children owing to possible eccrine glands immaturity.
弗雷综合征是一组症状，包括进食或饮用某些食物后单侧出汗伴面颊部及外耳发红。它是一种继发于手术、腮腺感染或面部创伤的耳颞神经病变。
三名年龄在4岁至2岁半之间的儿童，两名女孩和一名男孩。他们有自限性的单侧面部红斑，可延伸至外耳，无皮疹、瘙痒、血管性水肿及胃肠道或呼吸道症状；其发作与食用酸性及一些甜食有关。在耳颞神经走行部位观察到症状再现。他们的病史包括因头盆不称行剖宫产（病例1）、产钳助产阴道分娩（病例2）以及因先兆子痫行剖宫产（病例3）。
弗雷综合征常被误诊为食物过敏，导致不必要的饮食限制。由于可能存在小汗腺不成熟，儿童出汗情况往往不明显。
