[宫颈癌患者血清中的冷淋巴细胞毒性抗体]

[Cold-lymphocytotoxic antibodies in the sera of cervix-carcinoma patients].

作者信息

Müller N, Koenig U D

出版信息

Blut. 1977 Jun;34(6):479-83. doi: 10.1007/BF00996875.

Abstract

Sera of 120 patients with cervical cancer were screened for cold reacting, complement dependant autolympho-cytotoxins (CoCoCy). These antibodies occurred in 21,7% of the patients in comparison with 11,2% of 116 controls. The highest percentage of CoCoCy-antibodies was detected in the sera of patients with cervical cancer stage I (27,6%). Thus demonstration of CoCoCy-antibodies may be of pathogenetic rather than of diagnostic interest. CoCoCy-antibodies could be seen to reflect autoimmune reactions in cervical cancer.

摘要

对120例宫颈癌患者的血清进行检测，以筛查冷反应性、补体依赖性自身淋巴细胞毒素（CoCoCy）。这些抗体在21.7%的患者中出现，而116例对照者中的出现率为11.2%。在I期宫颈癌患者血清中检测到的CoCoCy抗体比例最高（27.6%）。因此，CoCoCy抗体的检测可能在发病机制方面而非诊断方面具有意义。可以看出，CoCoCy抗体反映了宫颈癌中的自身免疫反应。