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藻酸盐/大豆蛋白体系包封精油并实现肠道传递。

Alginate/soy protein system for essential oil encapsulation with intestinal delivery.

机构信息

University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia.

University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia.

出版信息

Carbohydr Polym. 2018 Nov 15;200:15-24. doi: 10.1016/j.carbpol.2018.07.033. Epub 2018 Jul 20.

Abstract

Preparation of alginate-soy protein isolate (AL/SPI) complex beads containing essential oil of thyme was carried out by emulsification of thyme oil in aqueous sodium alginate solution blended with SPI solution, followed by atomization via electrostatic extrusion and gelification with calcium ions. The process parameters were optimized by variation of the alginate (1-2.5 wt.%) and SPI (0-1.5 wt.%) concentrations. Dry alginate-SPI particles exhibited wrinkle surface while shape distortion of hydrogel beads occurred with ≥1.5 wt.% alginate concentration, whereas SPI induced reduction of the particle size. Encapsulation efficiency of 72-80 % based on total polyphenols was achieved. In SGF the samples exhibited oil release of 42-55 % (due to matrix shrinkage and proteins degradation by pepsin activity), while the rest was delivered in SIF within 2.5 h simultaneously with swelling and degradation of the matrix.

摘要

通过将百里香油乳化在含有大豆分离蛋白(SPI)溶液的海藻酸钠溶液中,然后通过静电挤压雾化和钙离子凝胶化,制备含有百里香油的藻酸盐-大豆分离蛋白(AL/SPI)复合微球。通过改变海藻酸钠(1-2.5wt.%)和 SPI(0-1.5wt.%)浓度来优化工艺参数。干燥的藻酸盐-SPI 颗粒表现出皱纹表面,而当海藻酸钠浓度≥1.5wt.%时水凝胶珠的形状发生变形,而 SPI 则导致颗粒尺寸减小。基于总多酚的包封效率为 72-80%。在 SGF 中,样品的油释放率为 42-55%(由于基质收缩和胃蛋白酶活性导致蛋白质降解),而其余的在 2.5h 内同时在 SIF 中释放,同时伴随着基质的溶胀和降解。

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