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老年人袖状胃切除术的中期结果。

Midterm outcomes of sleeve gastrectomy in the elderly.

机构信息

Surgery B Department, Carmel Medical Center, Haifa, Israel.

Surgery B Department, Carmel Medical Center, Haifa, Israel.

出版信息

Surg Obes Relat Dis. 2018 Oct;14(10):1495-1500. doi: 10.1016/j.soard.2018.07.020. Epub 2018 Jul 29.

Abstract

BACKGROUND

The increase in life expectancy presents health systems with a growing challenge in the form of elderly obesity. Bariatric surgery has been shown to be a safe and effective treatment for obesity with reduction of excess weight and improvement in obesity-related co-morbidities. However, only recently have surgeons begun performing these operations on elderly patients on a larger scale, making data regarding mid- and long-term outcomes scarce. The objective of this study was to evaluate the safety and midterm efficacy of laparoscopic sleeve gastrectomy (LSG) in patients aged ≥60 years.

METHODS

All patients aged ≥60 years who underwent LSG between 2008 and 2014 and achieved ≥24-month follow-up were retrospectively reviewed. Demographic characteristics and perioperative data were analyzed. Weight loss parameters and co-morbidity resolution rates were compared with preoperative data.

RESULTS

In total 55 patients aged ≥60 years underwent LSG. Mean patient age was 63.9 ± 3.2 years (range, 60-75.2), and mean preoperative body mass index was 43 ± 6.0 kg/m. Perioperative morbidity included 5 cases of hemorrhage necessitating operative exploration, 2 cases of reduced hemoglobin levels treated with blood transfusion, and 1 case of portal vein thrombosis managed with anticoagulation. There were no mortalities. Mean follow-up time was 48.6 (range, 25.6-94.5) months. Mean percentage of excess weight loss was 66.4 ± 19.7, 67.5 ±1 6.4, 61.4 ± 18.3, 66.7 ± 25.6, 50.7 ± 21.4 at 12, 24, 36, 37 to 60, and 61 to 96 months, respectively. Statistically significant improvement of type 2 diabetes, hypertension, and dyslipidemia were observed at the latest follow-up (P < .01).

CONCLUSION

LSG offers an effective treatment of obesity and its co-morbidities in patients aged ≥60 years, albeit with a high perioperative bleeding rate at our center; efficacy is maintained for at least 4.5 years.

摘要

背景

预期寿命的增加给医疗系统带来了一个越来越大的挑战,即老年肥胖。减重手术已被证明是一种安全有效的肥胖治疗方法,可减轻体重过重,并改善与肥胖相关的合并症。然而,最近外科医生才开始在更大范围内对老年患者进行这些手术,这使得关于中期和长期结果的数据很少。本研究的目的是评估腹腔镜袖状胃切除术(LSG)在年龄≥60 岁患者中的安全性和中期疗效。

方法

回顾性分析 2008 年至 2014 年间接受 LSG 且随访时间≥24 个月的年龄≥60 岁患者。分析人口统计学特征和围手术期数据。比较体重减轻参数和合并症缓解率与术前数据。

结果

共有 55 例年龄≥60 岁的患者接受了 LSG。患者平均年龄为 63.9±3.2 岁(范围为 60-75.2 岁),平均术前体重指数为 43±6.0kg/m。围手术期并发症包括 5 例需要手术探查的出血,2 例血红蛋白水平降低需输血治疗,1 例门静脉血栓形成采用抗凝治疗。无死亡病例。平均随访时间为 48.6 个月(范围为 25.6-94.5 个月)。术后 12、24、36、37 至 60、61 至 96 个月时,患者的体重超标减轻百分比分别为 66.4±19.7、67.5±16.4、61.4±18.3、66.7±25.6、50.7±21.4,呈逐渐下降趋势。随访时,2 型糖尿病、高血压和血脂异常的改善有统计学意义(P<0.01)。

结论

LSG 为年龄≥60 岁的肥胖患者及其合并症提供了一种有效的治疗方法,但我们中心的围手术期出血率较高;疗效至少可维持 4.5 年。

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