University of São Paulo Medical School (FMUSP), São Paulo, Brazil.
Clin Nucl Med. 2018 Nov;43(11):848-849. doi: 10.1097/RLU.0000000000002259.
F-fluoride (F-NaF) uptake in soft tissue metastases of medullary thyroid carcinoma (MTC) has been reported. However, the evolution of these metastatic sites has rarely been assessed. We present a case of F-NaF uptake in multiple liver metastases of MTC initially without macroscopic calcification. The CT follow-up studies showed a progressive calcium deposition in the lesions. Therefore, this case suggests that the F-NaF uptake in MTC metastases could potentially be a marker of an ongoing calcification process instead of an inert deposit of calcium.
氟-18 氟化钠（F-NaF）在甲状腺髓样癌（MTC）的软组织转移灶中的摄取已有报道。然而，这些转移灶的演变很少被评估。我们报告了一例 MTC 多发性肝转移灶摄取 F-NaF 的病例，最初无肉眼可见的钙化。CT 随访研究显示病变内钙沉积逐渐增加。因此，该病例提示 MTC 转移灶摄取 F-NaF 可能是正在进行的钙化过程的标志物，而不是钙的惰性沉积。
