Kwon Ohyuk, Chung Joonho
Department of Neurosurgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
J Korean Neurosurg Soc. 2021 Jan;64(1):23-29. doi: 10.3340/jkns.2020.0054. Epub 2020 Aug 7.
Although stent-assisted coiling (SAC) has been reported to be safe and effective in treating wide-necked aneurysms, the technique has procedure-related complications. Thus, we reported our experiences of SAC using the Neuroform Atlas stent in treating wide-necked aneurysms and evaluated the incidence of and risk factors for procedure-related complications.
From March 2018 to August 2019, we treated 130 unruptured wide-necked aneurysms in 123 patients with Neuroform Atlas stents. Angiographic results and clinical outcomes were reviewed retrospectively. Clinical and angiographic follow-up were performed in all cases (mean, 12.4 months) after the procedure.
There were eight cases (6.2%) of procedure-related complications (two dissections, five thromboembolisms, and one hemorrhage) and two (1.5%) of delayed complications (one ischemia and one hemorrhage). There was one case (0.8%) of failure of stent deployment and one (0.8%) of suboptimal positioning of the stent. Follow-up angiography showed complete obliteration in 103 (79.2%), residual neck in 16 (12.3%), and residual aneurysm in 11 cases (8.5%). Aneurysm locations in the middle cerebral artery (odds ratio [OR], 2.211; p=0.046) and the anterior communicating artery (OR, 2.850; p=0.039) were associated with procedurerelated complications on univariate analysis. However, no independent risk factor for procedure-related complications was noted in multivariate analysis.
The Neuroform Atlas showed a high rate of technical success. Good clinical and radiographic outcomes in early follow-up suggests that the device is feasible and safe. SAC of aneurysms on the middle cerebral artery or anterior communicating artery may require more attention to prevent possible procedure-related complications.
尽管有报道称支架辅助弹簧圈栓塞术(SAC)在治疗宽颈动脉瘤方面安全有效,但该技术存在与手术相关的并发症。因此,我们报告了使用Neuroform Atlas支架进行SAC治疗宽颈动脉瘤的经验,并评估了与手术相关并发症的发生率及危险因素。
2018年3月至2019年8月,我们使用Neuroform Atlas支架治疗了123例患者的130个未破裂宽颈动脉瘤。对血管造影结果和临床结局进行回顾性分析。术后对所有病例(平均12.4个月)进行临床和血管造影随访。
有8例(6.2%)发生与手术相关的并发症(2例夹层、5例血栓栓塞和1例出血),2例(1.5%)发生延迟并发症(1例缺血和1例出血)。有1例(0.8%)支架置入失败,1例(0.8%)支架定位欠佳。随访血管造影显示103例(79.2%)完全闭塞,16例(12.3%)有残余颈部,11例(8.5%)有残余动脉瘤。单因素分析显示,大脑中动脉(优势比[OR],2.211;p=0.046)和前交通动脉(OR,2.850;p=0.039)的动脉瘤位置与手术相关并发症有关。然而,多因素分析未发现与手术相关并发症的独立危险因素。
Neuroform Atlas显示出较高的技术成功率。早期随访良好的临床和影像学结果表明该装置可行且安全。大脑中动脉或前交通动脉动脉瘤的SAC可能需要更多关注以预防可能的手术相关并发症。