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一种罕见的临床表现:多形性黄色星形细胞瘤伴脑内出血且转移迅速——病例报告及文献综述

A rare clinical presentation: a pleomorphic xanthoastrocytoma presenting with intracerebral haemorrhage and metastasizing vigorously-case report and review of the literature.

作者信息

Demirci Otluoğlu Gülden, Özek M Memet

机构信息

Division of Pediatric Neurosurgery, Acıbadem University School of Medicine, Altunizade Mah. Yurtcan Sk. NO:1, 34662, Üsküdar/İstanbul, Turkey.

出版信息

Childs Nerv Syst. 2019 Feb;35(2):355-362. doi: 10.1007/s00381-018-3960-1. Epub 2018 Sep 4.

Abstract

Metastasis of an intracranial tumour is not a common situation in our daily neurosurgical practice. Pleomorphic xanthoastrocytoma is also a rare glial tumour with relatively a favourable prognosis among other CNS pathologies. Here, we present an anaplastic pleomorphic xanthoastrocytoma case which shows both haematogenous and lymphatic metastasis which is described first time in the up-to-date literature. Our case is a 17-year-old male operated for a right occipital intra-axial lesion with a diagnosis of anaplastic pleomorphic xanthoastrocytoma which recurs 5 years later and metastasize vigorously through haematogenous and lymphatic routes. A rare-presenting symptom for this pathology is also intracerebral haemorrhage. This is the ninth case report in the literature which presents initially with this entity.

摘要

在我们日常的神经外科实践中,颅内肿瘤转移并不常见。多形性黄色星形细胞瘤也是一种罕见的胶质瘤,在其他中枢神经系统病变中预后相对较好。在此,我们报告一例间变性多形性黄色星形细胞瘤病例,该病例同时出现血行转移和淋巴转移,这在最新文献中尚属首次描述。我们的病例是一名17岁男性,因右枕叶轴内病变接受手术,诊断为间变性多形性黄色星形细胞瘤,5年后复发并通过血行和淋巴途径迅速转移。该病理罕见的表现症状还包括脑内出血。这是文献中第九例最初表现为此种病症的病例报告。

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