Jie Zhang, Zenghe Yin, Xiaolei Zhang, Yong Zhu
Opt Express. 2018 Sep 3;26(18):23534-23539. doi: 10.1364/OE.26.023534.
Quantitative surface-enhanced Raman scattering (SERS) in practical applications still remain unresolved, mainly due to low reproducibility relying on the quality of the SERS substrates. In this paper, a carbon nanotube and Ag nanoparticles composite (CNT/AgNPs) is reported, and the carbon nanotube is as an internal standard for the calibration of SERS intensity of analyte molecules. The quantification of analyte molecules rhodamine 6G (R6G) is demonstrated in an aqueous solution with the concentration of 10-9 to 10-7 M. Raman mapping is used to investigate the stability of SERS spectra in a large scanning area, and the corresponding relative standard deviation (RSD) is calculated. SERS mapping reveals that the uniformity of Raman enhancement is improved through the build-in calibration with 2D Raman peak of CNT. Meanwhile, CNT/AgNPs samples are used to detect N2 in natural air, indicating that such self-calibration method can improve the reliability of the SERS analysis.
定量表面增强拉曼散射（SERS）在实际应用中仍未得到解决，主要是因为其重现性低，依赖于SERS基底的质量。本文报道了一种碳纳米管与银纳米颗粒复合材料（CNT/AgNPs），其中碳纳米管用作校准分析物分子SERS强度的内标。在浓度为10⁻⁹至10⁻⁷M的水溶液中对分析物分子罗丹明6G（R6G）进行了定量分析。利用拉曼映射研究了大扫描区域内SERS光谱的稳定性，并计算了相应的相对标准偏差（RSD）。SERS映射表明，通过利用碳纳米管的二维拉曼峰进行内置校准，拉曼增强的均匀性得到了改善。同时，使用CNT/AgNPs样品检测自然空气中的N₂，表明这种自校准方法可以提高SERS分析的可靠性。
