SiO 微球阵列涂覆 Ag 纳米粒子作为具有高灵敏度和高稳定性的 Raman 增强传感器。

SiO Microsphere Array Coated by Ag Nanoparticles as Raman Enhancement Sensor with High Sensitivity and High Stability.

机构信息

The Key Laboratory of Optoelectronic Technology & System (Ministry of Education), Chongqing University, Chongqing 400044, China.

出版信息

Sensors (Basel). 2022 Jun 17;22(12):4595. doi: 10.3390/s22124595.

In this paper, a monolayer SiO microsphere (MS) array was self-assembled on a silicon substrate, and monolayer dense silver nanoparticles (AgNPs) with different particle sizes were transferred onto the single-layer SiO MS array using a liquid-liquid interface method. A double monolayer "Ag@SiO" with high sensitivity and high uniformity was prepared as a surface-enhanced Raman scattering (SERS) substrate. The electromagnetic distribution on the Ag@SiO substrate was analyzed using the Lumerical FDTD (finite difference time domain) Solutions software and the corresponding theoretical enhancement factors were calculated. The experimental results show that a Ag@SiO sample with a AgNPs diameter of 30 nm has the maximal electric field value at the AgNPs gap. The limit of detection (LOD) is 10 mol/L for Rhodamine 6G (R6G) analytes and the analytical enhancement factor (AEF) can reach ~2.3 × 10. Our sample also shows high uniformity, with the calculated relative standard deviation (RSD) of ~5.78%.

本文在硅衬底上自组装了单层 SiO 微球（MS）阵列，并采用液-液界面法将不同粒径的单层致密银纳米颗粒（AgNPs）转移到单层 SiO MS 阵列上。制备了具有高灵敏度和高均匀性的双层“Ag@SiO”作为表面增强拉曼散射（SERS）基底。使用 Lumerical FDTD（有限差分时间域）解决方案软件分析了 Ag@SiO 基底上的电磁场分布，并计算了相应的理论增强因子。实验结果表明，AgNPs 直径为 30nm 的 Ag@SiO 样品在 AgNPs 间隙处具有最大的电场值。罗丹明 6G（R6G）分析物的检测限（LOD）为 10 摩尔/升，分析增强因子（AEF）可达~2.3×10。我们的样品还表现出高均匀性，计算得到的相对标准偏差（RSD）约为 5.78%。