Kingston T, Collier S, Hevey D, McCormick M M, Besani C, Cooney J, O'Dwyer A M
1Department of Psychological Medicine,St James's Hospital,James St. Dublin 8,Ireland.
Ir J Psychol Med. 2015 Sep;32(3):265-274. doi: 10.1017/ipm.2014.81.
Mindfulness-based cognitive therapy (MBCT) is a group-based intervention similar to mindfulness-based stress reduction, but which includes cognitive therapy techniques. This study investigates its usefulness in the treatment of depressive, anxiety and stress/distress symptoms in cancer patients referred to a psycho-oncology service. It also examines whether effect on depression is mediated by self-compassion.
In phase 1 of this study, 16 cancer patients with mild/moderate psychological distress were randomised to MBCT (n=8) or treatment as usual (TAU; n=8), and assessed pre- and post-treatment. Analysis of variance was performed to examine the effect of treatment on anxiety and depression. In phase 2, the TAU group received the intervention, and results of pre- and post-MBCT assessments were combined with those receiving MBCT in phase 1. Finally, both groups were followed up at 3 months.
In phase 1, the MBCT group had a significant improvement in mindfulness and a decrease in anxiety. Statistically significant improvements in both depression and anxiety were found at 3 month follow-up. Self-compassion appeared to mediate the effect on anxiety/depression.
This small pilot study suggests that MBCT may have a beneficial effect on psychological variables often adversely affected in cancer in a heterogeneous cancer population.
基于正念的认知疗法(MBCT)是一种基于团体的干预措施,类似于基于正念的减压疗法,但包含认知疗法技术。本研究调查其在治疗转介至心理肿瘤服务机构的癌症患者的抑郁、焦虑和压力/痛苦症状方面的有效性。研究还探讨对抑郁的影响是否通过自我同情来介导。
在本研究的第1阶段,16名有轻度/中度心理困扰的癌症患者被随机分为MBCT组(n = 8)或常规治疗组(TAU;n = 8),并在治疗前后进行评估。采用方差分析来检验治疗对焦虑和抑郁的影响。在第2阶段,TAU组接受干预,将MBCT治疗前后的评估结果与第1阶段接受MBCT治疗的结果合并。最后,两组均在3个月时进行随访。
在第1阶段,MBCT组在正念方面有显著改善,焦虑有所降低。在3个月的随访中,抑郁和焦虑均有统计学意义的显著改善。自我同情似乎介导了对焦虑/抑郁的影响。
这项小型试点研究表明,MBCT可能对异质性癌症人群中通常受到癌症不利影响的心理变量产生有益作用。