Lin Li-Ying, Lin Li-Hua, Tzeng Ghao-Ling, Huang Ya-Hui, Tai Jui-Fen, Chen Yu-Ling, Wu Chia-Jung, Chen Pin-Hsi, Lin Pei-Chin, Hung Pi-Lien
Department of Nursing, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Department of Nursing, Meiho University, Pingtung, Taiwan.
J Clin Psychol Med Settings. 2022 Jun;29(2):432-445. doi: 10.1007/s10880-022-09862-z. Epub 2022 Mar 6.
This meta-analysis was a systematic review of evidence on the effects of mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) on quality of life (QOL), pain, fatigue, anxiety, and depression in cancer patients. Until July 2020, PubMed, Cochrane Library, and Embase were searched for randomized controlled trials (RCTs). The study included 18 RCTs. The MBSR/MBCT intervention resulted in a significant effect on QOL (SMD 0.80, CI 0.28, 1.32, I = 94%). In subgroup analysis, MBSR/MBCT interventions had a significant effect in the early cancer stage on anxiety (SMD - 3.48, CI - 4.07, - 2.88), and QOL (SMD 4.30, CI 3.62, 4.99); in alleviating decreasing pain (SMD - 0.42, CI - 0.70, - 0.14) within 4 weeks after the end of intervention, and alleviating fatigue in younger participants (SMD - 0.64, CI - 1.09, - 0.19). MBSR/MBCT has short-term effects on cancer patients, especially in younger patients and early cancer stages.
这项荟萃分析是对基于正念减压疗法（MBSR）和基于正念认知疗法（MBCT）对癌症患者生活质量（QOL）、疼痛、疲劳、焦虑和抑郁影响的证据进行的系统评价。截至2020年7月，检索了PubMed、Cochrane图书馆和Embase数据库中的随机对照试验（RCT）。该研究纳入了18项RCT。MBSR/MBCT干预对生活质量有显著影响（标准化均数差[SMD]0.80，95%置信区间[CI]0.28，1.32，I² = 94%）。在亚组分析中，MBSR/MBCT干预在癌症早期对焦虑（SMD - 3.48，CI - 4.07，- 2.88）和生活质量（SMD 4.30，CI 3.62，4.99）有显著影响；在干预结束后4周内减轻疼痛（SMD - 0.42，CI - 0.70，- 0.14），并减轻年轻参与者的疲劳（SMD - 0.64，CI - 1.09，- 0.19）。MBSR/MBCT对癌症患者有短期影响，尤其是在年轻患者和癌症早期阶段。
