Fakoya Adegbenro Omotuyi John, Otohinoyi David Adeiza, Omole Adekunle Ebenezer, Oladele Charles, Kalejaiye Ayoola, Onuegbu Angel, Nwalie Esther, Talukdar Debjyoti, Erinkitola Omowaninuola
Department of Anatomical Sciences, University of Medicine and Health Sciences, St. Kitts and Nevis; Department of Anatomical Sciences, School of Medicine, All Saints University, Roseau, Dominica.
Medical Student, School of Medicine, All Saints University, Roseau, Dominica.
Ann Afr Med. 2018 Jul-Sep;17(3):133-139. doi: 10.4103/aam.aam_51_17.
The aortic root is an aggregate of various components that connects the left ventricle to the aorta. The most predominant pathologies have been associated with the dilation of the aortic root leading to aneurysms.
This study is designed to measure the role of systemic morbidities such as hypertension, diabetes, and body mass index (BMI) on the dimension of the aortic root.
Participants were volunteers of African descent who were recruited during and after an organized health fair by the medical students' body from All Saints University, School of Medicine. 169 participants consisting of 62 males and 107 females with ages ranging from 9 to 84 years agreed to volunteer by signing the consent after which a questionnaire was administered and a preliminary clinical procedure was used to check for blood pressure (BP), blood glucose (BG), and BMI. The measurement of the aortic root was carried out by an experienced single investigator who was not aware of the purpose of measurements, using a DUS-5000 ultrasound machine (Miami, Florida, USA) at a low-frequency micro-convex transducer preset to "adult cardiac" with a default frequency of 4 MHz.
Among the participants, 35.03%, 47.80%, and 29.11% had normal BP, BG, and BMI readings, respectively. The Chi-squared analysis identified a significant correlation between the diameter of the aortic annulus (AA) and BMI. Diastolic BP is also correlated with the diameter of the AA. Sinus of Valsalva (SV) showed an unusual correlation with BG as opposed to BP and BMI.
The disparity in how a systemic factor individually correlates with the AA and the SV is not clear. The study targets to provide educational concept in this regard.
主动脉根部是连接左心室与主动脉的各种组织的集合。最主要的病变与主动脉根部扩张导致动脉瘤有关。
本研究旨在衡量高血压、糖尿病和体重指数（BMI）等全身性疾病对主动脉根部尺寸的影响。
参与者为非洲裔志愿者，由来自圣徒大学医学院的医学生群体在一次有组织的健康博览会期间及之后招募。169名参与者（62名男性和107名女性，年龄在9至84岁之间）签署同意书后自愿参与，之后进行问卷调查，并采用初步临床程序检查血压（BP）、血糖（BG）和BMI。主动脉根部的测量由一名经验丰富的单一研究者进行，该研究者不知道测量目的，使用DUS - 5000超声仪（美国佛罗里达州迈阿密），低频微凸探头预设为“成人心脏”，默认频率为4兆赫。
参与者中，分别有35.03%、47.80%和29.11%的人血压、血糖和BMI读数正常。卡方分析确定主动脉瓣环（AA）直径与BMI之间存在显著相关性。舒张压也与AA直径相关。与血压和BMI不同，主动脉窦（SV）与血糖呈现出不同寻常的相关性。
全身性因素与AA和SV各自的相关性差异尚不清楚。该研究旨在提供这方面的教育理念。
