Ptashne M
Nature. 1986;322(6081):697-701. doi: 10.1038/322697a0.
Transcription of genes can be controlled by regulatory proteins that bind to sites on the DNA either nearby or at a considerable distance. Recent experiments suggest a unified view of these apparently disparate types of gene regulation.
基因的转录可以由与DNA上附近或相当远距离位点结合的调节蛋白来控制。最近的实验提出了对这些明显不同类型的基因调控的统一观点。