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Pyridazinyl-GABA derivatives as GABA and glycine antagonists in the spinal cord of the cat.

作者信息

Gynther B D, Curtis D R

出版信息

Neurosci Lett. 1986 Jul 24;68(2):211-5. doi: 10.1016/0304-3940(86)90144-8.

Abstract

Of two arylaminopyridazine derivatives of gamma-aminobutyric acid (GABA) tested as antagonists of the inhibitory actions of glycine and GABA in the spinal cord of pentobarbitone-anaesthetized cats, one - SR95531 - was sufficiently selective to be of use in microelectrophoretic investigations of GABA-mediated synaptic transmission.

摘要

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