Kupeli Ilke, Tepe Emine, Kuyrukluyıldız Ufuk
Department of Anesthesiology and Reanimation, Erzincan Binali Yıldırım University, Faculty Of Medicine, Erzincan, Turkey.
J Dent Anesth Pain Med. 2018 Aug;18(4):261-265. doi: 10.17245/jdapm.2018.18.4.261. Epub 2018 Aug 28.
Rett syndrome (RS) is a neurodevelopmental disorder characterized by loss of cognitive, motor, and social skills, epilepsy, autistic behavior, abnormal airway patterns, gastroesophageal reflux, nutritional problems, and severe scoliosis. Although girls with RS show normal or near-normal growth until 6-8 months, they lose their skills after that. The anesthetic management of these patients requires care because of all these clinical features. Especially in the postoperative period, prolonged apnea is common and extubation is delayed. In this case report, the effect of using sugammadex was presented in a 16-year-old girl with RS. The patient's all bimaxillary teeth and 4 wisdom teeth were extracted under general anesthesia in one session with minimal surgical trauma and moderate bleeding. Sugammadex can be a rapid and reliable agent for the reversal of the neuromuscular block in neurodegenerative patients.
雷特综合征（RS）是一种神经发育障碍，其特征为认知、运动和社交技能丧失、癫痫、自闭症行为、异常气道模式、胃食管反流、营养问题以及严重脊柱侧弯。尽管患有RS的女孩在6至8个月前生长正常或接近正常，但此后她们会丧失这些技能。由于所有这些临床特征，对这些患者的麻醉管理需要格外小心。特别是在术后阶段，长时间呼吸暂停很常见，拔管也会延迟。在本病例报告中，介绍了舒更葡糖在一名16岁雷特综合征女孩中的应用效果。该患者的所有双侧上颌牙齿和4颗智齿在全身麻醉下一次性拔除，手术创伤最小且出血适中。舒更葡糖可能是用于逆转神经退行性疾病患者神经肌肉阻滞的一种快速且可靠的药物。
