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指南评估项目:填补外科指南中的空白:国际工作组的质量改进倡议。

Guideline Assessment Project: Filling the GAP in Surgical Guidelines: Quality Improvement Initiative by an International Working Group.

机构信息

Department of Colorectal Surgery, Royal Devon and Exeter NHS Foundation Trust, Exeter, United Kingdom.

Exeter Surgical Health Services Research Unit, Royal Devon and Exeter Hospital, Exeter, United Kingdom.

出版信息

Ann Surg. 2019 Apr;269(4):642-651. doi: 10.1097/SLA.0000000000003036.

Abstract

OBJECTIVE

The aim of the study was to identify clinical practice guidelines published by surgical scientific organizations, assess their quality, and investigate the association between defined factors and quality. The ultimate objective was to develop a framework to improve the quality of surgical guidelines.

SUMMARY BACKGROUND DATA

Evidence on the quality of surgical guidelines is lacking.

METHODS

We searched MEDLINE for clinical practice guidelines published by surgical scientific organizations with an international scope between 2008 and 2017. We investigated the association between the following factors and guideline quality, as assessed using the AGREE II instrument: number of guidelines published within the study period by a scientific organization, the presence of a guidelines committee, applying the GRADE methodology, consensus project design, and the presence of intersociety collaboration.

RESULTS

Ten surgical scientific organizations developed 67 guidelines over the study period. The median overall score using AGREE II tool was 4 out of a maximum of 7, whereas 27 (40%) guidelines were not considered suitable for use. Guidelines produced by a scientific organization with an output of ≥9 guidelines over the study period [odds ratio (OR) 3.79, 95% confidence interval (CI), 1.01-12.66, P = 0.048], the presence of a guidelines committee (OR 4.15, 95% CI, 1.47-11.77, P = 0.007), and applying the GRADE methodology (OR 8.17, 95% CI, 2.54-26.29, P < 0.0001) were associated with higher odds of being recommended for use.

CONCLUSIONS

Development by a guidelines committee, routine guideline output, and adhering to the GRADE methodology were found to be associated with higher guideline quality in the field of surgery.

摘要

目的

本研究旨在确定外科科学组织发布的临床实践指南,评估其质量,并研究已确定因素与质量之间的关联。最终目标是制定一个框架来提高外科指南的质量。

背景资料摘要

缺乏关于外科指南质量的证据。

方法

我们在 2008 年至 2017 年间,在 MEDLINE 上搜索了具有国际范围的外科科学组织发布的临床实践指南。我们调查了以下因素与指南质量之间的关联,使用 AGREE II 工具评估:在研究期间,一个科学组织发布的指南数量、指南委员会的存在、应用 GRADE 方法、共识项目设计以及是否存在协会间合作。

结果

在研究期间,有 10 个外科科学组织制定了 67 条指南。使用 AGREE II 工具的总体中位数得分为 4 分(满分 7 分),其中 27 条(40%)指南不适合使用。在研究期间,一个科学组织发布的指南数量≥9 条的情况下[比值比(OR)3.79,95%置信区间(CI)1.01-12.66,P = 0.048]、存在指南委员会(OR 4.15,95%CI,1.47-11.77,P = 0.007)和应用 GRADE 方法(OR 8.17,95%CI,2.54-26.29,P < 0.0001)与更高的推荐使用可能性相关。

结论

指南委员会的制定、常规指南的产出以及遵循 GRADE 方法与外科领域指南的更高质量相关。

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