1 Luskin School of Public Affairs, University of California, Los Angeles, Los Angeles, CA, USA.
2 RAND Corporation, Santa Monica, CA, USA.
Public Health Rep. 2018 Sep/Oct;133(5):559-569. doi: 10.1177/0033354918781085.
The objective of our study was to assess meningococcal ACWY (MenACWY) vaccine uptake among men who have sex with men (MSM) during an ongoing, invasive meningococcal disease outbreak in Southern California. This research was important to inform future vaccination uptake interventions for this high-priority population.
We conducted venue-based sampling to recruit and enroll MSM living in Los Angeles County, California, from December 2016 through February 2017. We conducted bivariate and multivariable analyses to evaluate associations between MenACWY vaccine uptake and other predetermined factors.
Of 368 participants, 138 (37.5%) reported receiving the MenACWY vaccine. In multivariable analyses, older age (adjusted odds ratio [aOR] = 2.57; 95% confidence interval [CI], 1.31-5.03), previous diagnosis of a sexually transmitted infection (aOR = 2.22; 95% CI, 1.14-4.30), belief that MenACWY vaccine is important (aOR = 3.49; 95% CI, 1.79-6.82), confidence in the MenACWY vaccine (aOR = 5.53; 95% CI, 3.11-9.83), and knowing someone who had been vaccinated (aOR = 5.82; 95% CI, 3.05-11.12) were significantly associated with MenACWY vaccine uptake.
Our findings reflect low uptake of the recommended MenACWY vaccine among MSM after a local outbreak, despite public health efforts. In addition to ongoing, widespread campaigns to inform MSM about local outbreaks and vaccination recommendations, MSM may be responsive to direct outreach from peers who have been vaccinated.
我们的研究目的是评估在南加州持续发生侵袭性脑膜炎奈瑟菌病爆发期间，男男性行为者（MSM）中脑膜炎球菌 ACWY（MenACWY）疫苗的接种情况。这项研究对于为这一高优先级人群提供未来的疫苗接种干预措施非常重要。
我们进行了基于场所的抽样，以招募并纳入 2016 年 12 月至 2017 年 2 月期间居住在加利福尼亚州洛杉矶县的 MSM。我们进行了双变量和多变量分析，以评估 MenACWY 疫苗接种与其他预定因素之间的关联。
在 368 名参与者中，有 138 名（37.5%）报告接种了 MenACWY 疫苗。在多变量分析中，年龄较大（调整后的优势比[aOR] = 2.57；95%置信区间[CI]，1.31-5.03）、以前诊断过性传播感染（aOR = 2.22；95%CI，1.14-4.30）、认为 MenACWY 疫苗很重要（aOR = 3.49；95%CI，1.79-6.82）、对 MenACWY 疫苗有信心（aOR = 5.53；95%CI，3.11-9.83）和认识已经接种过疫苗的人（aOR = 5.82；95%CI，3.05-11.12）与 MenACWY 疫苗接种显著相关。
尽管公共卫生部门做出了努力，但在当地爆发后，我们的研究结果反映出 MSM 对接种推荐的 MenACWY 疫苗的接受率较低。除了持续开展广泛的宣传活动，让 MSM 了解当地疫情和疫苗接种建议外，直接向已经接种疫苗的同龄人提供帮助，MSM 可能会做出响应。
