Xing Juan, Reynolds Jordan P
University of Pittsburgh Medical Center, UPMC Shadyside Hospital, 5150 Centre Avenue, POB2, Suite 201.2, Pittsburgh, PA 15232, USA.
Cleveland Clinic Foundation, Pathology and Laboratory Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Surg Pathol Clin. 2018 Sep;11(3):601-610. doi: 10.1016/j.path.2018.06.001. Epub 2018 Jul 13.
The utility of urine cytology has shifted from the identification of red blood cells, crystals, or parasites to its currently used role of detection of cancer cells exfoliated in urine samples. A variety of ancillary tests have been developed to complement the diagnostic ability of urine cytology. Furthermore, urine testing will continue to evolve as the pathogenesis of genitourinary tract diseases in depth is understood. This article focuses on the diagnostic advances in urine cytology from the cytomorphological perspective, past and current reporting schemes, and the application of ancillary testing in urine samples.
尿液细胞学的用途已从识别红细胞、晶体或寄生虫转变为目前用于检测尿液样本中脱落癌细胞的作用。已经开发了多种辅助检测方法来补充尿液细胞学的诊断能力。此外,随着对泌尿生殖道疾病发病机制的深入了解,尿液检测将不断发展。本文从细胞形态学角度、过去和当前的报告方案以及辅助检测在尿液样本中的应用等方面,重点介绍尿液细胞学的诊断进展。