Uzunoglu Mustafa Yener, Altintoprak Fatih, Dikicier Enis, Zengin Ismail
Mustafa Yener Uzunoglu, MD. Department of General Surgery, Sakarya University, Research and Educational Hospital, Sakarya, Turkey.
Fatih Altintoprak, MD. Department of General Surgery, Istinye University Faculty of Medicine, Istanbul, Turkey. Department of General Surgery, Sakarya University, Research and Educational Hospital, Sakarya, Turkey.
Pak J Med Sci. 2018 Jul-Aug;34(4):974-979. doi: 10.12669/pjms.344.14808.
Although non-traumatic Small Bowel Perforations (SBPs) are rare, they have high rates of morbidity and mortality in case of late presentation. Aetiological factors vary across different geographical regions. In this paper, SBPs caused by anything other than trauma and other well-known causes are presented and the current literature is reviewed.
The study was conducted at General Surgery Clinics of two different tertiary university hospitals between January 2008 and September 2016. The authors directly involved in managing the patients. This study was approved by the ethical institutional board and was performed at the Department of General Surgery, School of Medicine, Sakarya University. The medical records of patients retained in both hospitals are electronic. Medical records of subjects who had undergone emergency operations with a prediagnosis of acute abdomen in single center, and were determined to have SBPs due to unusual causes, were investigated retrospectively. Patients with aetiological factors such as trauma, mesenteric vascular disease, internal and external hernias, intra abdominal adhesions, inflammatory bowel diseases, and iatrogenic causes were excluded.
In total, 35 patients were evaluated, 20 (57.1%) males and 15 (42.9%) females. The mean age of the cases was 51.6 (18-88) years. Mean time until admission at the hospital was 1.4 days (range 0.25-7 days). The most frequent aetiological factors were various malignancies (10 cases, 28.5%) and perforation of Meckel's diverticulum (8 cases, 22.8%). It was surprising to detect a considerable rate of perforation due to bezoars (6 patients, 17.1%).
Post-operative consequences of SBPs due to unusual causes are similar with those related to common, known causes. Factors affecting the clinical course are presentation time and patients' clinical status in admission, not aetiology.
非创伤性小肠穿孔(SBP)虽罕见,但延迟就诊时发病率和死亡率很高。不同地理区域的病因各不相同。本文介绍了由创伤及其他已知病因以外的因素导致的SBP,并对当前文献进行综述。
2008年1月至2016年9月期间,在两所不同的三级大学医院的普通外科诊所开展该研究。作者直接参与患者管理。本研究经机构伦理委员会批准,在萨卡里亚大学医学院普通外科进行。两所医院留存的患者病历均为电子病历。回顾性调查在单中心因急性腹痛预诊断而接受急诊手术、且因不寻常病因被确诊为SBP的患者的病历。排除有创伤、肠系膜血管疾病、内外疝、腹腔内粘连、炎症性肠病和医源性病因等病因的患者。
共评估了35例患者,其中男性20例(57.1%),女性15例(42.9%)。病例的平均年龄为51.6岁(18 - 88岁)。入院前平均时间为1.4天(范围0.25 - 7天)。最常见病因是各种恶性肿瘤(10例,28.5%)和梅克尔憩室穿孔(8例,22.8%)。因胃石导致穿孔的比例相当高(6例,17.1%),这令人惊讶。
由不寻常病因导致的SBP术后后果与常见已知病因导致的相似。影响临床病程的因素是就诊时间和入院时患者的临床状况,而非病因。