Khasina E I, Kirillov O I
Acta Physiol Hung. 1986;67(4):435-9.
Triphasic changes in glycogen content and activities of four enzymes of carbohydrate metabolism (glucose-6-phosphatase, phosphoenolpyruvate carboxykinase, hexokinase, and glucose-6-phosphate dehydrogenase) were studied in the liver of male Wistar rats exposed to 1, 5, 10, 15, 20, 30, 45, 60, 70 and 90-day movement restrain in pencil cases. It was assumed that these three phases corresponded to the alarm, resistance and exhaustion stages of Selye's general adaptation syndrome. In hypokinetic rats, however, a transition of the alarm reaction to the resistance stage was registered later, and hepatic glycogen accumulation was reduced in comparison with the standard pattern observed in chronic stress.
在置于铅笔盒中经历1、5、10、15、20、30、45、60、70和90天运动限制的雄性Wistar大鼠肝脏中，研究了糖原含量以及四种碳水化合物代谢酶（葡萄糖-6-磷酸酶、磷酸烯醇式丙酮酸羧激酶、己糖激酶和葡萄糖-6-磷酸脱氢酶）活性的三相变化。假定这三个阶段分别对应于塞利氏一般适应综合征的警觉、抵抗和衰竭阶段。然而，在运动不足的大鼠中，警觉反应向抵抗阶段的转变出现得较晚，并且与慢性应激中观察到的标准模式相比，肝糖原积累减少。
