脑酸提取物产品对近交系小鼠3H-地西泮受体的影响
[Effect of brain acid extract products in inbred mice on 3H-diazepam reception].
作者信息
Blednov Iu A, Fedoseev Iu L, Bogdanov N N, Gordeĭ M L, Seredenin S B
出版信息
Biull Eksp Biol Med. 1986 Sep;102(9):294-6.
PMID:3019448
Abstract
The influence of brain acid extract products, isolated by high-performance liquid chromatography on H3-diazepam binding was investigated in synaptosomal membranes of C57BL/6 and BALB/c mice. Fractions with stimulatory and inhibitory activity were isolated. Quantitative and qualitative differences in the effects and structure of ACTH-immunoreactive peptide fractions under study were established.
摘要
研究了通过高效液相色谱法分离的脑酸提取物产品对C57BL/6和BALB/c小鼠突触体膜中H3-地西泮结合的影响。分离出具有刺激和抑制活性的组分。确定了所研究的促肾上腺皮质激素免疫反应性肽组分在作用和结构上的定量和定性差异。
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