Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024, Negrar, Italy.
Aix Marseille Univ, AP-HM, SSA, VITROME, IHU-Méditerranée Infection, 19-21 Bd Jean Moulin, 13005, Marseille, France.
Travel Med Infect Dis. 2018 Nov-Dec;26:58-61. doi: 10.1016/j.tmaid.2018.08.008. Epub 2018 Sep 6.
In Italy, the incidence of tick-borne diseases in humans is underestimated, as they are not obligatorily notifiable. The aim of this study was to investigate the presence of tick-borne pathogens in ticks removed from human subjects in Veneto region (northeastern Italy), an area for which no published studies are yet available.
Forty-five ticks prospectively removed from human subjects, between March and August 2016, were analysed for bacterial DNA.
Seven of 45 ticks were infected with bacteria, including human pathogens: 4 Rickettsia spp. (9%), including R. monacensis and R. helvetica; 3 Borrelia spp. and 1 Anaplasma phagocytophilum. Three subjects bitten by infected ticks reported symptoms.
Rickettsiosis and anaplasmosis, tick-borne diseases previously not considered in northeastern Italy, should not be neglected. A new survey for a longer period is required to obtain stronger epidemiological data.
在意大利，由于 ticks-borne 疾病并非强制性报告疾病，因此人类感染 ticks-borne 疾病的发病率被低估。本研究旨在调查从意大利东北部威尼托地区（Veneto region）的人体上取下的 ticks 中是否存在 ticks-borne 病原体，目前尚无针对该地区的已发表研究。
2016 年 3 月至 8 月期间，前瞻性地从 45 名人体上取下的 ticks 中提取细菌 DNA 进行分析。
45 只 ticks 中有 7 只感染了细菌，包括人类病原体：4 种 Rickettsia 属（9%），包括 R. monacensis 和 R. helvetica；3 种 Borrelia 属和 1 种 Anaplasma phagocytophilum。3 名被感染 ticks 叮咬的患者出现了症状。
以前在意大利东北部未被认为是 ticks-borne 的疾病，如立克次体病和无形体病，不应被忽视。需要进行更长时间的新调查以获得更强有力的流行病学数据。
