Ingham Institute for Applied Medical Research, Department of Medical Physics, Liverpool, Australia; Liverpool Cancer Therapy Centre, Radiation Physics, Liverpool, Australia; University of New South Wales, School of Medicine, Sydney, Australia; Centre for Medical Radiation Physics, University of Wollongong, Australia.
University of Sydney, ACRF ImageX Institute, Sydney Medical School, Australia.
Clin Oncol (R Coll Radiol). 2018 Nov;30(11):686-691. doi: 10.1016/j.clon.2018.08.003. Epub 2018 Sep 6.
The desire to utilise soft-tissue image guidance at the time of radiation treatment has led to the development of several hybrid magnetic resonance imaging (MRI) linear accelerators (linacs). These systems have the potential to realise the benefits of MRI on the treatment table with the ability of real-time motion management and adaption on a patient-specific basis. There are several MRI-linacs currently being implemented covering both low and high magnetic field strength and two beam-field orientations. Clinical trials have only recently begun with this technology, but their future use as standard radiotherapy practice seems assured. This review article summarises the challenges faced in developing such hybrid technology, the differences and advantages of each of the currently exploited solutions, and their current status.
利用软组织图像引导在放射治疗时，已经开发出了几种混合磁共振成像（MRI）直线加速器（linacs）。这些系统有可能在治疗台上实现 MRI 的优势，具有实时运动管理和基于患者个体的适应性的能力。目前有几种低磁场和高磁场强度的 MRI- linacs 正在实施中，并且有两种射束-场方向。这项技术最近才开始临床试验，但它们作为标准放射治疗实践的未来用途似乎已经确定。本文综述了开发这种混合技术所面临的挑战，目前利用的解决方案的差异和优势，以及它们的现状。
