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[摄入椰子水或肉三明治后胃内容物体积的超声动力学。一项在健康志愿者中的随机对照交叉研究]

[Ultrasound dynamics of gastric content volumes after the ingestion of coconut water or a meat sandwich. A randomized controlled crossover study in healthy volunteers].

作者信息

Carmona Bruno Mendes, Almeida Clauber Claudino Alves, Vieira Waldônio de Brito, Fascio Mario de Nazareth Chaves, Carvalho Lídia Raquel de, Vane Luiz Antonio, Barbosa Fabiano Timbó, do Nascimento Junior Paulo, Módolo Norma Sueli Pinheiro

机构信息

Hospital Ophir Loyola, Departamento de Anestesiologia, Belém, PA, Brasil.

Hospital Ophir Loyola, Departamento de Anestesiologia, Belém, PA, Brasil.

出版信息

Braz J Anesthesiol. 2018 Nov-Dec;68(6):584-590. doi: 10.1016/j.bjan.2018.06.008. Epub 2018 Sep 6.

Abstract

BACKGROUND

Adequate preoperative fasting is critical in preventing pulmonary aspiration of gastric content. We proposed to study the sonographic gastric content dynamics after the ingestion of liquid or solid food in healthy volunteers and confront it with current guidelines for preoperative fasting times.

METHODS

We performed a prospective, crossover, evaluator-blinded study involving 17 healthy volunteers of both sexes. Each participant fasted for 10 h and was subjected to a baseline gastric ultrasound, intake of 400 mL of coconut water or a 145 g, 355 kcal meat sandwich, and sonographic gastric evaluations after 10 min and every hour until the stomach was completely empty.

RESULTS

At baseline, all subjects had an empty stomach. At 10 min, gastric content [mean + standard deviation (SD)] was 240.4 + 69.3 and 248.2 + 119.2 mL for liquid and solid foods, respectively ( > 0.05). Mean + SD gastric emptying times were 2.5 + 0.7 and 4.5 + 0.9 h for liquid and solid foods, respectively ( < 0.001). For the drink, the stomach was completely empty in 59% and 100% of the subjects after two and four hours, and for the sandwich, 65% and 100% of the subjects after four and seven hours, respectively.

CONCLUSIONS

Sonographic gastric dynamics for coconut water and a meat sandwich resulted in complete gastric emptying times higher and lower, respectively, than those suggested by current guidelines for preoperative fasting.

摘要

背景

充分的术前禁食对于预防胃内容物的肺误吸至关重要。我们提议研究健康志愿者摄入液体或固体食物后胃内容物的超声动态变化,并将其与当前的术前禁食时间指南进行对比。

方法

我们进行了一项前瞻性、交叉、评估者盲法研究,纳入了17名健康的男女志愿者。每位参与者禁食10小时,然后进行基线胃超声检查,接着摄入400毫升椰子水或一个145克、355千卡的肉三明治,并在10分钟后及之后每小时进行超声胃评估,直至胃完全排空。

结果

基线时,所有受试者的胃均为空胃。10分钟时,液体和固体食物的胃内容物[平均值+标准差(SD)]分别为240.4 + 69.3毫升和248.2 + 119.2毫升(P>0.05)。液体和固体食物的平均+ SD胃排空时间分别为2.5 + 0.7小时和4.5 + 0.9小时(P<0.001)。对于饮料,分别有59%和100%的受试者在两小时和四小时后胃完全排空;对于三明治,分别有65%和100%的受试者在四小时和七小时后胃完全排空。

结论

椰子水和肉三明治的超声胃动态变化导致胃完全排空时间分别高于和低于当前术前禁食指南所建议的时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d89e/9391824/b87b2dd3d2b4/gr1.jpg

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