Jia Huixian, Feng Chenghong, Tian Chenhao
State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University.
Anal Sci. 2018;34(9):1079-1083. doi: 10.2116/analsci.18P036.
A new Cr probe was synthesized using simple Schiff base reaction, which showed prominent fluorescence increasing switch before and after addition Cr. The probe proved to have excellent properties, based on both UV-vis absorption and fluorescence spectra. Those properties included high switching performance, good selectivity, and small interference with other metal ions. The fluorescent change mechanism of the probe was attributed to the combined action between the restricted C=N isomerization and the suppression of highly efficient photo-induced electron transfer (PET) process. Moreover, this fluorescence probe for Cr detection also has great potential for bioimaging of cancer cells.
通过简单的席夫碱反应合成了一种新型的Cr探针，该探针在添加Cr前后显示出显著的荧光增强开关。基于紫外可见吸收光谱和荧光光谱，该探针具有优异的性能。这些性能包括高开关性能、良好的选择性以及对其他金属离子的干扰小。探针的荧光变化机制归因于受限的C=N异构化和高效光诱导电子转移（PET）过程的抑制之间的联合作用。此外，这种用于检测Cr的荧光探针在癌细胞的生物成像方面也具有巨大潜力。
