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与肾结石病相关的非典型菌血症和尿路感染

Nontypable Septicemia and Urinary Tract Infection Associated with Renal Stone Disease.

作者信息

Stærk Marianne, Tolouee Sara A, Christensen Jens J

机构信息

Department of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark.

Department of Urology, Zealand University Hospital Roskilde, Roskilde, Denmark.

出版信息

Open Microbiol J. 2018 Jul 31;12:243-247. doi: 10.2174/1874285801812010243. eCollection 2018.

Abstract

INTRODUCTION

commonly causes upper respiratory tract infections and has only rarely been reported etiology of urinary tract infections. Since the introduction of the b (Hib) vaccine, non-typable species now cause the majority of invasive disease in Europe.

CASE REPORT

We report a case of an adult man with non-typable septicemia, urinary tract infection and bilateral renal stone disease. The patient presented with right sided flank pain and a CT scan showed bilateral renal stones and a right sided ureteral stone causing obstruction.

RESULTS AND DISCUSSION

was identified in blood and urine and despite a tendency of increasing antibiotic resistance among , our strain was susceptible to all antibiotics tested. Treatment consisted of 3 days of intravenous cefuroxime, insertion of a right sided JJ ureteric stent and 5 days of peroral ciprofloxacin after discharge. Physicians and microbiologists should be aware of as a possible urinary tract pathogen, especially when urinary tract abnormalities are present, and take the risk of antibiotic resistance into consideration at initial treatment.

摘要

引言

通常引起上呼吸道感染,而作为尿路感染的病因仅有极少报道。自b型流感嗜血杆菌(Hib)疫苗引入以来,不可分型菌株目前在欧洲导致了大多数侵袭性疾病。

病例报告

我们报告一例成年男性患者,患有不可分型菌败血症、尿路感染和双侧肾结石病。患者出现右侧胁腹疼痛,CT扫描显示双侧肾结石以及右侧输尿管结石导致梗阻。

结果与讨论

在血液和尿液中检测到该菌,尽管该菌的抗生素耐药性有增加趋势,但我们的菌株对所有测试抗生素敏感。治疗包括静脉注射头孢呋辛3天,插入右侧双J输尿管支架,出院后口服环丙沙星5天。医生和微生物学家应意识到该菌可能是尿路病原体,尤其是当存在尿路异常时,并在初始治疗时考虑抗生素耐药的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/266b/6110053/441f91d48a62/TOMICROJ-12-243_F1.jpg

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