De Jesus-Rojas Wilfredo, Mosquera Ricardo A, Samuels Cheryl, Eapen Julie, Gonzales Traci, Harris Tomika, McKay Sandra, Boricha Fatima, Pedroza Claudia, Aneji Chiamaka, Khan Amir, Jon Cindy, McBeth Katrina, Stark James, Yadav Aravind, Tyson Jon E
Division of Pulmonary Medicine/Allergy & Immunology/Rheumatology, Department of Pediatrics, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA.
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA.
Open Respir Med J. 2018 Jul 31;12:39-49. doi: 10.2174/1874306401812010039. eCollection 2018.
Survival of infants with complex care has led to a growing population of technology-dependent children. Medical technology introduces additional complexity to patient care. Outcomes after NICU discharge comparing Usual Care (UC) with Comprehensive Care (CC) remain elusive.
To compare the outcomes of technology-dependent infants discharged from NICU with tracheostomy following UC versus CC.
A single site retrospective study evaluated forty-three (N=43) technology-dependent infants discharged from NICU with tracheostomy over 5½ years (2011-2017). CC provided 24-hour accessible healthcare-providers using an enhanced medical home. Mortality, total hospital admissions, 30-days readmission rate, time-to-mechanical ventilation liberation, and time-to-decannulation were compared between groups.
CC group showed significantly lower mortality (3.4%) versus UC (35.7%), RR, 0.09 [95%CI, 0.12-0.75], P=0.025. CC reduced total hospital admissions to 78 per 100 child-years versus 162 for UC; RR, 0.48 [95% CI, 0.25-0.93], P=0.03. The 30-day readmission rate was 21% compared to 36% in UC; RR, 0.58 [95% CI, 0.21-1.58], P=0.29). In competing-risk regression analysis (treating death as a competing-risk), hazard of having mechanical ventilation removal in CC was two times higher than UC; SHR, 2.19 [95% CI, 0.70-6.84]. There was no difference in time-to-decannulation between groups; SHR, 1.09 [95% CI, 0.37-3.15].
CC significantly decreased mortality, total number of hospital admissions and length of time-to-mechanical ventilation liberation.
对需要复杂护理的婴儿进行救治,使得依赖技术的儿童群体不断壮大。医疗技术给患者护理带来了更多复杂性。关于新生儿重症监护病房(NICU)出院后常规护理(UC)与综合护理(CC)的效果仍不明确。
比较NICU出院的依赖技术且行气管造口术的婴儿接受UC与CC后的结局。
一项单中心回顾性研究评估了5年半(2011 - 2017年)期间从NICU出院的43名依赖技术且行气管造口术的婴儿。CC通过强化医疗之家提供24小时可及的医疗服务提供者。比较两组之间的死亡率、总住院次数、30天再入院率、机械通气脱机时间和拔管时间。
CC组死亡率(3.4%)显著低于UC组(35.7%),相对危险度(RR)为0.09 [95%置信区间(CI),0.12 - 0.75],P = 0.025。CC将总住院次数降至每100儿童年78次,而UC为162次;RR为0.48 [95% CI,0.25 - 0.93],P = 0.03。30天再入院率为21%,而UC为36%;RR为0.58 [95% CI,0.21 - 1.58],P = 0.29)。在竞争风险回归分析(将死亡视为竞争风险)中,CC组机械通气撤除的风险比UC组高两倍;标准化危险比(SHR)为2.19 [95% CI,0.70 - 6.84]。两组之间拔管时间无差异;SHR为1.09 [95% CI,0.37 - 3.15]。
CC显著降低了死亡率、总住院次数和机械通气脱机时间。